CTSV and KCNJ1

Data Source:
BioGRID (affinity chromatography technology)

		CTSV	KCNJ1
Description		cathepsin V	potassium inwardly rectifying channel subfamily J member 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Lysosome Lysosomal Lumen	Plasma Membrane Voltage-gated Potassium Channel Complex
	Molecular Function	Cysteine-type Endopeptidase Activity Protein Binding Cysteine-type Peptidase Activity	Inward Rectifier Potassium Channel Activity ATP Binding Phosphatidylinositol-4,5-bisphosphate Binding ATP-activated Inward Rectifier Potassium Channel Activity
	Biological Process	Immune Response Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Extracellular Matrix Disassembly Regulation Of Keratinocyte Differentiation Proteolysis Involved In Cellular Protein Catabolic Process	Potassium Ion Transport Excretion Regulation Of Ion Transmembrane Transport Potassium Ion Import Across Plasma Membrane
Pathways		Endosomal/Vacuolar pathway Degradation of the extracellular matrix Activation of Matrix Metalloproteinases Trafficking and processing of endosomal TLR Assembly of collagen fibrils and other multimeric structures MHC class II antigen presentation RUNX1 regulates transcription of genes involved in differentiation of keratinocytes	Potassium transport channels
Drugs		3-amino-5-phenylpentane 4-Methylpiperazin-1-Yl Carbonyl Group	Bethanidine Glimepiride Minoxidil Acetohexamide Tolbutamide Glymidine Yohimbine Agmatine Butamben
Diseases			Bartter syndrome
GWAS
Interacting Genes		13 interacting genes: APC BMPR1A BRAF BUB1 CDKN2A CTNNA1 DCC DLC1 MLH1 MLH3 PDGFRL RB1 SRC	6 interacting genes: GOLGA3 PRKCD SGK1 SH3RF1 SLC9A3R1 SLC9A3R2
Entrez ID		1515	3758
HPRD ID		04495	08981
Ensembl ID		ENSG00000136943	ENSG00000151704
Uniprot IDs		A0A024R141 B2R717 O60911	A0A024R3K6 A8K432 P48048
PDB IDs		1FH0 3H6S 3KFQ
Enriched GO Terms of Interacting Partners?
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