METTL21A and GIGYF2

Data Source:
BioGRID (proximity labelling technology)

		METTL21A	GIGYF2
Description		methyltransferase like 21A	GRB10 interacting GYF protein 2
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Protein-containing Complex	Endosome Endoplasmic Reticulum Golgi Apparatus Cytosol Cytoplasmic Stress Granule Membrane Protein-containing Complex Perikaryon Proximal Dendrite
	Molecular Function	Protein Binding Protein Methyltransferase Activity Protein-lysine N-methyltransferase Activity Hsp70 Protein Binding Heat Shock Protein Binding ATPase Binding	RNA Binding Protein Binding Cadherin Binding Proline-rich Region Binding
	Biological Process	Protein Methylation Peptidyl-lysine Methylation Regulation Of ATPase Activity	Posttranscriptional Gene Silencing Negative Regulation Of Translation Insulin-like Growth Factor Receptor Signaling Pathway MRNA Destabilization
Pathways		Protein methylation
Drugs
Diseases			Parkinson's disease (PD)
GWAS		HDL cholesterol levels ( 32203549) Opioid sensitivity ( 23183491) Systolic blood pressure ( 28135244 28739976 30578418)	Anxiety and stress-related disorders ( 31116379) Autism spectrum disorder or schizophrenia ( 28540026) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Coronary artery disease ( 32469254 29212778 33020668) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Schizophrenia ( 25056061 29483656 23974872)
Interacting Genes		15 interacting genes: ARPC4 ATRIP HSPA1A HSPA5 HSPA8 LNX1 LZTS1 MEI4 MEOX2 MSRB3 PFDN5 ZBED8 ZNF620 ZNF655 ZRANB1	8 interacting genes: APC CNOT9 GRB10 GRB14 GRB7 RBM12 SNRPB WBP11
Entrez ID		151194	26058
HPRD ID		14090	11639
Ensembl ID		ENSG00000144401	ENSG00000204120
Uniprot IDs		C9JES0 H7BXH9 Q8WXB1	Q6Y7W6
PDB IDs		4LEC	5NVL 5NVM
Enriched GO Terms of Interacting Partners?
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