CTNNA1 and CDH3

Data Source:
HPRD (in vivo)

		CTNNA1	CDH3
Description		catenin alpha 1	cadherin 3
Image
GO Annotations	Cellular Component	Acrosomal Vesicle Cytosol Plasma Membrane Cell-cell Junction Adherens Junction Zonula Adherens Focal Adhesion Intercalated Disc Actin Cytoskeleton Catenin Complex Flotillin Complex Lamellipodium Cell Junction Intracellular Membrane-bounded Organelle	Cytoplasm Plasma Membrane Adherens Junction Integral Component Of Membrane Catenin Complex Cell Junction
	Molecular Function	RNA Binding Structural Molecule Activity Protein Binding Beta-catenin Binding Vinculin Binding Identical Protein Binding Gamma-catenin Binding Cadherin Binding Actin Filament Binding	Molecular_function Calcium Ion Binding Cadherin Binding
	Biological Process	Ovarian Follicle Development Actin Filament Organization Cell Adhesion Establishment Or Maintenance Of Cell Polarity Negative Regulation Of Neuroblast Proliferation Aging Male Gonad Development Gap Junction Assembly Cell Migration Axon Regeneration Adherens Junction Organization Cellular Protein Localization Odontogenesis Of Dentin-containing Tooth Apical Junction Assembly Response To Estrogen Positive Regulation Of Smoothened Signaling Pathway Positive Regulation Of Muscle Cell Differentiation Cellular Response To Indole-3-methanol Epithelial Cell-cell Adhesion Cell-cell Adhesion Negative Regulation Of Protein Localization To Nucleus Negative Regulation Of Cell Motility Negative Regulation Of Integrin-mediated Signaling Pathway Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand	Retina Homeostasis Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Visual Perception Positive Regulation Of Gene Expression Positive Regulation Of Keratinocyte Proliferation Hair Cycle Process Keratinization Positive Regulation Of Monophenol Monooxygenase Activity Negative Regulation Of Transforming Growth Factor Beta2 Production Adherens Junction Organization Wound Healing Response To Drug Positive Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Positive Regulation Of Melanin Biosynthetic Process Negative Regulation Of Timing Of Catagen Regulation Of Hair Cycle By Canonical Wnt Signaling Pathway Positive Regulation Of Canonical Wnt Signaling Pathway Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Positive Regulation Of Melanosome Transport
Pathways		Adherens junctions interactions VEGFR2 mediated vascular permeability Myogenesis Myogenesis RHO GTPases activate IQGAPs	Adherens junctions interactions
Drugs
Diseases			Hypotrichosis, congenital, with juvenile macular dystrophy Ectodermal dysplasia, ectrodactyly, and macular dystrophy (EEM syndrome)
GWAS		General risk tolerance (MTAG) ( 30643258) Malaria ( 31844061) Schizophrenia ( 25056061)	Cutaneous melanoma or hair colour ( 32341527) Glycated hemoglobin levels ( 28898252) Mean reticulocyte volume ( 32888494) Multiple sclerosis ( 31604244 24076602) Platelet count ( 32888494) Red cell distribution width ( 27863252) Ulcerative colitis ( 28067908)
Interacting Genes		52 interacting genes: ACTN1 AFDN AJUBA AKT1 ALDOB APC APP ARMC8 BAAT CA9 CCDC180 CDC42 CDH1 CDH15 CDH2 CDH3 CDH5 CSNK2A1 CTBP1 CTNNB1 CTSV DLG1 F2RL1 FBP1 FBP2 FRAT2 HRAS HSD17B3 JUP LRATD2 MAP2K1 MTNR1A MTNR1B NANS OBI1 PKD1 PSEN1 SASH1 SFRP2 SFRP4 SMAD1 SPTAN1 SPTBN1 STX17 TDRD7 TJP1 TJP2 UBE2I VCL ZGPAT ZNF189 ZNF510	3 interacting genes: CTNNA1 CTNNB1 CTNND1
Entrez ID		1495	1001
HPRD ID		00285	00227
Ensembl ID		ENSG00000044115	ENSG00000062038
Uniprot IDs		A0A384MDY0 B4DKT9 B4DU00 G3XAM7 P35221	B4DLF0 P22223
PDB IDs		1H6G 4EHP 4IGG 6UPV 6V2O 6V2P	4OY9 4ZML 4ZMN 4ZMO 4ZMP 4ZMQ 4ZMT 4ZMV 4ZMW 4ZMX 4ZMY 4ZMZ 5JYL 5JYM
Enriched GO Terms of Interacting Partners?
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