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CTBP2 and HOXA5
Data Source:
BioGRID
(two hybrid)
CTBP2
HOXA5
Description
C-terminal binding protein 2
homeobox A5
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Transcription Repressor Complex
Photoreceptor Ribbon Synapse
Presynaptic Active Zone Cytoplasmic Component
Glutamatergic Synapse
GABA-ergic Synapse
Presynaptic Cytosol
Chromatin
Nucleus
Molecular Function
RNA Polymerase II Transcription Corepressor Binding
Chromatin Binding
Transcription Coactivator Activity
Transcription Corepressor Activity
Protein Binding
Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor
Protein Kinase Binding
Retinoic Acid Receptor Binding
Protein-containing Complex Binding
NAD Binding
Structural Constituent Of Presynaptic Active Zone
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Cell Population Proliferation
Synaptic Vesicle Docking
Viral Genome Replication
Positive Regulation Of Chromatin Binding
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Retinoic Acid Receptor Signaling Pathway
Maintenance Of Presynaptic Active Zone Structure
White Fat Cell Differentiation
Cellular Response To Leukemia Inhibitory Factor
Respiratory System Process
Regulation Of Transcription By RNA Polymerase II
Anterior/posterior Pattern Specification
Positive Regulation Of Gene Expression
Cell Migration
Negative Regulation Of Angiogenesis
Thyroid Gland Development
Regulation Of Mammary Gland Epithelial Cell Proliferation
Multicellular Organism Growth
Positive Regulation Of Apoptotic Process
Positive Regulation Of Myeloid Cell Differentiation
Negative Regulation Of Erythrocyte Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Lung Alveolus Development
Embryonic Skeletal System Morphogenesis
Bronchiole Development
Epithelial Tube Branching Involved In Lung Morphogenesis
Lung Goblet Cell Differentiation
Lung-associated Mesenchyme Development
Trachea Cartilage Morphogenesis
Intestinal Epithelial Cell Maturation
Mesenchymal-epithelial Cell Signaling
Mammary Gland Epithelial Cell Differentiation
Mammary Gland Alveolus Development
Cell-cell Signaling Involved In Mammary Gland Development
Pathways
Repression of WNT target genes
Signaling by TCF7L2 mutants
Drugs
Diseases
GWAS
Adult body size (
32376654
)
Age-related cognitive decline (visuospatial skill) (slope of z-scores) (
30954325
)
Apolipoprotein A1 levels (
32203549
)
Body mass index (
25673413
29273807
)
Body size at age 10 (
32376654
)
Brain morphology (MOSTest) (
32665545
)
Chronotype (
30696823
)
Diastolic blood pressure (
30224653
)
HDL cholesterol levels (
32203549
)
Height (
25429064
)
Hemoglobin levels (
32327693
)
Infant, child and juvenile death in continuous marriage (proportion of children died <15 years) (
30188897
)
Menarche (age at onset) (
25231870
)
Oily fish consumption (
32066663
)
Pork consumption (
32066663
)
Prostate cancer (
18264096
)
Red blood cell count (
32888494
)
Refractive error (
32231278
)
Vigorous physical activity (
29899525
)
Chronic venous disease (
28374850
)
Interacting Genes
99 interacting genes:
ACTG1
AKTIP
APP
BAZ2B
BCAS3
BCL3
C15orf39
CACNB1
CACNB2
CACNB3
CACNB4
CAPN7
CASP8AP2
CATSPER1
CBX4
CCDC120
CCNH
CCR5
CDKN2A
CEP68
CSTF2
CTBP1
CTPS2
DMRTB1
DTNB
DUSP21
DVL2
EEF1D
EGLN3
EIF4G1
ELAC2
ENKD1
EP300
FHL3
FLI1
FOXP2
FUNDC1
GLIS2
H3-4
HEMGN
HIC1
HOXA5
HOXB5
HOXC5
IKZF1
IKZF2
KCNIP3
KLF3
KLF8
KYNU
LCORL
LMO4
MDM2
MECOM
MSRB3
NEK6
NOL4
NOL4L
NRIP1
PLCB1
PNN
PPP1R15A
PROX1
PSMF1
QARS1
RAI2
RBBP8NL
RIMBP3
RNF135
RPL17
RPL7A
RPS28
RPS29
RPS4X
SDCBP
SHISA6
SOX13
SOX6
STUB1
STX11
TEAD3
TGIF1
TLE5
TRIML2
TSHZ3
UBC
UBE2I
VRTN
XRCC6
ZBP1
ZBTB18
ZBTB42
ZEB1
ZEB2
ZFPM1
ZFPM2
ZNF512B
ZNF750
ZSCAN4
16 interacting genes:
CDX4
CTBP2
DDIT3
DNMT3L
DVL3
FOXA2
FOXO1
GTF2A1L
MEIS1
PBX1
PBX2
PICK1
PRMT6
SMAD1
TWIST1
ZNF408
Entrez ID
1488
3202
HPRD ID
04016
00840
Ensembl ID
ENSG00000175029
ENSG00000106004
Uniprot IDs
P56545
P20719
PDB IDs
2OME
4LCJ
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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