CSTF3 and CSTF2

Data Source:
BioGRID (biochemical, pull down, affinity chromatography technology, biochemical)
HPRD (in vitro)

		CSTF3	CSTF2
Description		cleavage stimulation factor subunit 3	cleavage stimulation factor subunit 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex Nuclear Body Cleavage Body
	Molecular Function	RNA Binding MRNA Binding Protein Binding	RNA Binding MRNA Binding Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription MRNA Polyadenylation MRNA Cleavage RNA 3'-end Processing MRNA 3'-end Processing	MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription MRNA Polyadenylation TRNA Splicing, Via Endonucleolytic Cleavage And Ligation MRNA 3'-end Processing Pre-mRNA Cleavage Required For Polyadenylation
Pathways		mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs	tRNA processing in the nucleus mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS		Anger ( 24489884) Non-response to citalopram or escitalopram and depression ( 27622933)
Interacting Genes		13 interacting genes: CSTF1 CSTF2 MIR128-2 MIR138-2 MIR15B MIR19A MIR19B1 MIR21 MIR92A2 MIRLET7A3 MIRLET7F2 MIRLET7G MIRLET7I	49 interacting genes: ABHD11 AKAP8L ANKRD10 APP ATP23 BAG6 CDSN CEACAM6 CEP126 CHD3 CNOT2 CSTF3 CTBP2 DDX1 ECH1 EEF1G ELP1 ERG28 FAM168B FEZ1 HDHD3 HGS IMMT INCA1 KAT5 METTL15 METTL27 MIR19A MIR92A2 POLR2A POU6F2 PPP1R32 PRDM6 RFX6 SPAG8 SS18L1 STH SUB1 SYMPK TFG TLE3 TLE5 TSC1 UBQLN1 UBQLN2 UBQLN4 UFSP1 USP54 ZNF341
Entrez ID		1479	1478
HPRD ID		02651	02652
Ensembl ID		ENSG00000176102	ENSG00000101811
Uniprot IDs		Q12996	B3V096 B4DUD5 E7EWR4 P33240
PDB IDs		6B3X 6URO	1P1T 2J8P 6Q2I 6TZE
Enriched GO Terms of Interacting Partners?
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