KLC3 and BBS5

Data Source:
BioGRID (two hybrid)

		KLC3	BBS5
Description		kinesin light chain 3	Bardet-Biedl syndrome 5
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Kinesin Complex Microtubule Motile Cilium Ciliary Rootlet Neuron Projection	Cytosol Axoneme Centriolar Satellite BBSome Ciliary Basal Body Ciliary Membrane
	Molecular Function	Protein Binding Microtubule Binding Kinesin Binding	RNA Polymerase II Repressing Transcription Factor Binding Protein Binding Phosphatidylinositol-3-phosphate Binding
	Biological Process	Axo-dendritic Transport	Heart Looping Visual Perception Protein Transport Melanosome Transport Motile Cilium Assembly Intracellular Transport Response To Stimulus Cilium Assembly
Pathways		MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins	BBSome-mediated cargo-targeting to cilium
Drugs
Diseases			Bardet-Biedl syndrome (BBS)
GWAS		Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971)	Iris heterochromicity ( 30895295)
Interacting Genes		42 interacting genes: ABI3 ATP23 BBS5 BICDL2 CBY2 CCNH CENPP CEP57L1 CROCC CT55 DTX2 GEM IHO1 IMP3 KDM1A KIF5A KIF5B KIF5C KLHL21 KRT13 KRT15 MBIP NDC80 NECAB2 NEFL PCBD2 PDE4DIP QARS1 SMARCB1 SNAP47 STX11 TCF4 TSNAX USHBP1 VPS52 WAC WASHC1 YWHAG YWHAH YWHAQ ZNF417 ZNF572	2 interacting genes: CRADD KLC3
Entrez ID		147700	129880
HPRD ID		03212	10353
Ensembl ID		ENSG00000104892	ENSG00000163093
Uniprot IDs		A0A024R0V3 Q6P597	A0A0S2Z626 Q8N3I7
PDB IDs			6XTB
Enriched GO Terms of Interacting Partners?
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