WIPF2 and DNMBP

Data Source:
HPRD (in vitro)

		WIPF2	DNMBP
Description		WAS/WASL interacting protein family member 2	dynamin binding protein
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Actin Filament Plasma Membrane	Golgi Apparatus Golgi Stack Cytoskeleton Cell-cell Junction Synapse Presynapse
	Molecular Function	Actin Binding Protein Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Actin Filament-based Movement Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis	Aging Regulation Of Cell Shape Intracellular Signal Transduction Regulation Of Catalytic Activity
Pathways		Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Asthma ( 31619474) Blond vs. brown/black hair color ( 30531825) Household income (MTAG) ( 31844048) PR interval in Tripanosoma cruzi seropositivity ( 24324551)	Stent thrombosis in response to clopidogrel treatment ( 32472697)
Interacting Genes		12 interacting genes: APBB1 DNMBP GRB2 ITSN2 NCK2 PFN1 SORBS3 TCERG1 TVP23A WAS WASL WWOX	20 interacting genes: ACTA1 ARHGAP17 BUB1B CDC42 CNN1 CYFIP2 DBN1 DNM1 ENAH EVL FASLG HSPA1B KHDRBS1 NCKAP1 RAC1 RAPH1 VASP WASF1 WASL WIPF2
Entrez ID		147179	23268
HPRD ID		18304	10918
Ensembl ID		ENSG00000171475	ENSG00000107554
Uniprot IDs		Q8TF74	A0A1B0GTX1 A0A1C7CYY6 B3KY33 Q6XZF7
PDB IDs			1UG1 1UHC 4CC2 4CC3 4CC4 4CC7 4GLM
Enriched GO Terms of Interacting Partners?
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