PRICKLE1 and JRK

Data Source:
BioGRID (two hybrid)

		PRICKLE1	JRK
Description		prickle planar cell polarity protein 1	Jrk helix-turn-helix protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Nuclear Membrane	Cellular_component Nucleus Cytoplasm Ribonucleoprotein Complex
	Molecular Function	Protein Binding Zinc Ion Binding	DNA Binding MRNA Binding Protein Binding
	Biological Process	Neural Tube Closure Protein Import Into Nucleus Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Aorta Development Negative Regulation Of Transcription, DNA-templated Wnt Signaling Pathway, Planar Cell Polarity Pathway Coronary Vasculature Development Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Cardiac Muscle Cell Myoblast Differentiation	Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways		Asymmetric localization of PCP proteins
Drugs
Diseases		Progressive myoclonic epilepsy (PME), including: Lafora disease (LBD); Unverricht-Lundborg disease (ULD); Neuronal ceroid lipofuscinoses (NCL); Type I sialidosis; Action myoclonus-renal failure syndrome (AMRF); Type III Gaucher disease (GD)
GWAS		Autoimmune thyroid diseases (Graves disease or Hashimoto's thyroiditis) ( 22922229) Blood urea nitrogen levels ( 31152163) Colorectal cancer ( 30529582 31826910) Endometrial cancer (Non-endometrioid histology) ( 30093612) Graves' disease ( 22922229) Heart failure ( 20445134) Hip circumference adjusted for BMI ( 28552196) Impulsivity (non-planning) ( 30718321) Inferior parietal cortex volume ( 31530798) Multiple sclerosis ( 31604244) Night sleep phenotypes ( 27126917) Parkinson's disease ( 27182965) Refractive error ( 32231278) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)	Urinary tract infection frequency ( 28928442)
Interacting Genes		7 interacting genes: BYSL JRK KIF9 PRPF31 SMURF2 UTP14C VIP	36 interacting genes: ALAS1 BYSL C2CD6 CCDC136 CCDC57 CDC37 CNKSR3 FAM161A FBXO17 GOLGA6L9 HSF2BP IFRD2 KDM1A KPNA6 LDOC1 LGALS14 MTUS2 PDZD4 PICK1 PRICKLE1 TFIP11 TPM4 TRIM23 TRIM41 TRIP10 TSGA10 TXK USP2 UTP14C ZBTB8A ZNF343 ZNF417 ZNF620 ZNF629 ZNF655 ZRANB1
Entrez ID		144165	8629
HPRD ID		16341	04442
Ensembl ID		ENSG00000139174	ENSG00000234616
Uniprot IDs		A0A024R0W7 B3KVG3 B3KVG6 Q96MT3	O75564
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?