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DYDC1 and PPP2R5D
Data Source:
BioGRID
(two hybrid)
DYDC1
PPP2R5D
Description
DPY30 domain containing 1
protein phosphatase 2 regulatory subunit B'delta
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Chromosome, Telomeric Region
MLL3/4 Complex
Set1C/COMPASS Complex
Protein Phosphatase Type 2A Complex
Nucleus
Nucleoplasm
Cytosol
Molecular Function
Protein Binding
Phosphoprotein Phosphatase Activity
Protein Binding
Protein Phosphatase Regulator Activity
Protein Phosphatase Activator Activity
Biological Process
Chromatin Silencing At Telomere
Histone H3-K4 Methylation
Protein Dephosphorylation
Signal Transduction
Nervous System Development
Negative Regulation Of Peptidyl-threonine Phosphorylation
Regulation Of Protein Autophosphorylation
Positive Regulation Of Protein Dephosphorylation
Regulation Of Phosphoprotein Phosphatase Activity
Pathways
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Integration of energy metabolism
PP2A-mediated dephosphorylation of key metabolic factors
DARPP-32 events
Degradation of beta-catenin by the destruction complex
Beta-catenin phosphorylation cascade
ERK/MAPK targets
ERKs are inactivated
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
CTLA4 inhibitory signaling
Platelet sensitization by LDL
Disassembly of the destruction complex and recruitment of AXIN to the membrane
Disassembly of the destruction complex and recruitment of AXIN to the membrane
Signaling by GSK3beta mutants
S33 mutants of beta-catenin aren't phosphorylated
S37 mutants of beta-catenin aren't phosphorylated
S45 mutants of beta-catenin aren't phosphorylated
T41 mutants of beta-catenin aren't phosphorylated
APC truncation mutants have impaired AXIN binding
AXIN missense mutants destabilize the destruction complex
Truncations of AMER1 destabilize the destruction complex
RHO GTPases Activate Formins
RAF activation
Negative regulation of MAPK pathway
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
Mitotic Prometaphase
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism
EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS
Estimated glomerular filtration rate (
31451708
)
Amyotrophic lateral sclerosis (sporadic) (
24529757
)
Estimated glomerular filtration rate (
31015462
)
Interacting Genes
33 interacting genes:
ARNT2
CCHCR1
CCNC
CEP57L1
DPY30
ENKD1
HDAC4
HGS
KRT75
LMO2
LNX1
MID2
MOS
NME5
PDZD4
PIK3R2
PKN1
POU6F2
PPP2R5D
PSMA1
TCHP
TEAD4
TFPT
TLE5
TSGA10IP
TXLNB
TXNDC9
USHBP1
USP2
VPS37C
VPS9D1
WAC
ZGPAT
18 interacting genes:
CHEK2
CLOCK
CRY1
CRY2
CSNK1E
CSNK2B
DELEC1
DYDC1
FSD2
HAND1
HAND2
PPFIA1
PPP2R1A
PPP2R1B
PPP4C
RORC
SGO1
USHBP1
Entrez ID
143241
5528
HPRD ID
14062
09039
Ensembl ID
ENSG00000170788
ENSG00000112640
Uniprot IDs
Q8WWB3
A0A024RD11
Q14738
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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