CRYBA4 and FHL5

Data Source:
BioGRID (two hybrid)

		CRYBA4	FHL5
Description		crystallin beta A4	four and a half LIM domains 5
Image
GO Annotations	Cellular Component	Cellular_component	Nucleus Z Disc
	Molecular Function	Molecular_function Structural Constituent Of Eye Lens Protein Binding Identical Protein Binding	Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Metal Ion Binding
	Biological Process	Lens Development In Camera-type Eye Visual Perception Camera-type Eye Development	Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases		Anophthalmia and microphthalmia (A/M)
GWAS			Cerebral blood flow ( 28627999) Coronary artery disease ( 29212778) Coronary heart disease ( 22319020) Headache ( 29397368) Metabolite levels ( 23823483) Migraine ( 22683712 27182965 23793025 27322543) Migraine - clinic-based ( 23793025) Migraine without aura ( 23793025 27322543) Night sleep phenotypes ( 27126917) Pulse pressure ( 30578418) Spatial memory ( 31596458)
Interacting Genes		13 interacting genes: C1orf94 CCDC33 CEP76 CRYBB1 CRYBB2 EFEMP1 FHL5 GLI1 IKZF3 MIF4GD PRR22 STX11 TRIP6	90 interacting genes: ABI2 ADAM12 ADAMTSL5 AGXT ANKRD55 ANKS1A BANP BBC3 BCL6B CATSPER1 CDC20B CFP CNNM3 COIL CREB1 CREM CRYBA2 CRYBA4 CTSZ DCDC2B DLGAP4 DMRT3 DNAL4 DTX2 FAM214B FAM71C FARS2 FEZF1 FHL2 GPS2 GSTP1 HAPLN2 HCK HDX HEY2 HOXA1 HOXB9 IL16 IP6K3 KIF17 KIR2DL4 LMO2 LRRC41 MAGOHB MISP MYOZ3 NEK6 NPDC1 NUFIP2 OTX1 PIN1 PLEKHA2 PLEKHN1 PPP1R18 PPP1R32 QRICH1 RAB26 RAB3IL1 RPS21 SAXO1 SCNM1 SDCBP SEC31A SHFL SLIT1 SMAD1 SPRY1 SRF TUSC2 TXN2 YPEL3 ZBTB16 ZNF124 ZNF131 ZNF23 ZNF250 ZNF251 ZNF408 ZNF417 ZNF440 ZNF446 ZNF564 ZNF581 ZNF587 ZNF613 ZNF688 ZNF764 ZNF766 ZNF792 ZNHIT1
Entrez ID		1413	9457
HPRD ID		00432	05497
Ensembl ID		ENSG00000196431	ENSG00000112214
Uniprot IDs		A0A097PIJ6 P53673	Q5TD97
PDB IDs		3LWK	1X68
Enriched GO Terms of Interacting Partners?
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