CRYBA1 and SPRR1B

Data Source:
BioGRID (affinity chromatography technology)

		CRYBA1	SPRR1B
Description		crystallin beta A1	small proline rich protein 1B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Cornified Envelope Cytoplasm Cytosol
	Molecular Function	Molecular_function Structural Constituent Of Eye Lens Protein Binding	Structural Molecule Activity
	Biological Process	Negative Regulation Of Cytokine Production Lens Development In Camera-type Eye Visual Perception Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Negative Regulation Of TOR Signaling Negative Regulation Of Protein Kinase B Signaling Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Anoikis	Epidermis Development Peptide Cross-linking Keratinocyte Differentiation Cornification
Pathways			Formation of the cornified envelope
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Depression ( 29700475) Mean reticulocyte volume ( 32888494) Night sleep phenotypes ( 27126917)	Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Inflammatory skin disease ( 25574825)
Interacting Genes		24 interacting genes: ARID5A BANF2 CELF6 CERK CHCHD2 CRYAA CRYAB CRYBB1 CRYBB2 CRYBB3 CYSRT1 FOXH1 HOXC8 KRTAP11-1 KRTAP13-2 KRTAP13-3 LASP1 NOXA1 PLEKHF2 PROP1 RBPMS RHOXF2 VAC14 YPEL3
Entrez ID		1411	6699
HPRD ID		00429	01648
Ensembl ID		ENSG00000108255	ENSG00000169469
Uniprot IDs		P05813	P22528
PDB IDs
Enriched GO Terms of Interacting Partners?
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