DYNLL2 and KIF2B

Data Source:
BioGRID (imaging technique)
HPRD (in vivo, in vitro)

		DYNLL2	KIF2B
Description		dynein light chain LC8-type 2	kinesin family member 2B
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Centrosome Cytosol Cytoplasmic Dynein Complex Microtubule Plasma Membrane Cilium Postsynaptic Density Membrane Dynein Complex Myosin V Complex Ciliary Tip 9+0 Non-motile Cilium Postsynapse Glutamatergic Synapse	Condensed Chromosome Kinetochore Nucleolus Centrosome Spindle Cytosol Kinesin Complex Microtubule Microtubule Cytoskeleton Intercellular Bridge Mitotic Spindle
	Molecular Function	Motor Activity Protein Binding Identical Protein Binding Protein-containing Complex Binding Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding Scaffold Protein Binding	Microtubule Motor Activity ATP Binding Microtubule Binding ATPase Activity
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Macroautophagy Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Intraciliary Transport Involved In Cilium Assembly Cilium Assembly Positive Regulation Of ATP-dependent Microtubule Motor Activity, Plus-end-directed	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Microtubule-based Movement Microtubule Depolymerization Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Cell Division Metaphase Plate Congression Regulation Of Chromosome Segregation
Pathways		Activation of BMF and translocation to mitochondria Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Macroautophagy MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) Intraflagellar transport RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase HCMV Early Events Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins COPI-dependent Golgi-to-ER retrograde traffic Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation Kinesins
Drugs
Diseases
GWAS		Blood protein levels ( 30072576)	Adult body size ( 32376654) Carotid intima media thickness x smoking interaction ( 32117412) Metabolite levels ( 23823483) Photic sneeze reflex ( 27182965) Type 2 diabetes ( 30297969)
Interacting Genes		35 interacting genes: BCL2L11 BMF C12orf40 C14orf119 DLGAP1 DNAL4 DPPA3 DYNC1I1 EWSR1 FAM117B GABARAPL2 GPHN GPRIN2 HDAC6 HMBOX1 HOMER3 IHO1 KANK2 MEOX2 MORN3 MYO5A OTUD6A PAK1 PKIA PKIG RASGRP3 SECISBP2L SKAP1 SMCP SPAG8 THAP10 TLK1 TPPP XIAP ZAR1	1 interacting genes: STAU1
Entrez ID		140735	84643
HPRD ID		06489	10053
Ensembl ID		ENSG00000264364	ENSG00000141200
Uniprot IDs		Q96FJ2	A0A140VKG5 Q8N4N8
PDB IDs		2XQQ 3P8M 4D07
Enriched GO Terms of Interacting Partners?
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Tagcloud (Intersection) ?