ASB6 and CHRNB1

Data Source:
BioGRID (two hybrid)

		ASB6	CHRNB1
Description		ankyrin repeat and SOCS box containing 6	cholinergic receptor nicotinic beta 1 subunit
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol	Integral Component Of Plasma Membrane Acetylcholine-gated Channel Complex Neuromuscular Junction Neuron Projection Synapse Integral Component Of Postsynaptic Specialization Membrane
	Molecular Function	Protein Binding	Protein Binding Channel Activity Ligand-gated Ion Channel Activity Acetylcholine Receptor Activity Acetylcholine-gated Cation-selective Channel Activity Neurotransmitter Receptor Activity Acetylcholine Binding Transmitter-gated Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential
	Biological Process	Protein Ubiquitination Intracellular Signal Transduction Post-translational Protein Modification	Postsynaptic Membrane Organization Skeletal Muscle Contraction Cation Transport Muscle Contraction Signal Transduction Chemical Synaptic Transmission Synaptic Transmission, Cholinergic Neuromuscular Synaptic Transmission Ion Transmembrane Transport Behavioral Response To Nicotine Regulation Of Membrane Potential Muscle Fiber Development Nervous System Process Excitatory Postsynaptic Potential
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases			Congenital myasthenic syndrome
GWAS			Brain morphology (MOSTest) ( 32665545) Emotional recognition ( 31596458) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Refractive error ( 32231278)
Interacting Genes		16 interacting genes: APP CHRNB1 DUSP23 FAM9B HOMEZ HOXB5 L3MBTL3 MOS POLR2A RNF41 SH2B2 TARS2 TCAP ZBTB42 ZNF587 ZNF655	3 interacting genes: ASB6 COPS6 RAPSN
Entrez ID		140459	1140
HPRD ID		10673	01156
Ensembl ID		ENSG00000148331	ENSG00000170175
Uniprot IDs		F6TX30 Q9NWX5	P11230
PDB IDs
Enriched GO Terms of Interacting Partners?
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