ASB11 and BIK

Data Source:
BioGRID (pull down)

		ASB11	BIK
Description		ankyrin repeat and SOCS box containing 11	BCL2 interacting killer
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GO Annotations	Cellular Component	Endoplasmic Reticulum Cytosol	Endomembrane System Integral Component Of Membrane Mitochondrial Membrane
	Molecular Function		Protein Binding
	Biological Process	Protein Ubiquitination Intracellular Signal Transduction Post-translational Protein Modification Positive Regulation Of Protein Catabolic Process	Apoptotic Process Male Gonad Development Apoptotic Mitochondrial Changes Positive Regulation Of Protein-containing Complex Assembly Regulation Of Apoptotic Process Positive Regulation Of Release Of Cytochrome C From Mitochondria
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		vascular endothelial growth factor D levels ( 25147954)	Prostate cancer ( 25939597 21743057) Prostate cancer (SNP x SNP interaction) ( 22219177)
Interacting Genes		6 interacting genes: BIK CUL5 ELOB ELOC RNF7 UBC	95 interacting genes: ADGRE2 ADIPOQ AIG1 ALG8 ANKRD46 APOD APP ASB11 BCL2 BCL2A1 BCL2L1 BCL2L10 BCL2L2 BMP10 BNIP3 BRICD5 BTN2A2 C14orf180 C3orf52 C4orf3 CD53 CD72 CLDN19 CMTM5 CMTM7 CNIH1 CNIH3 CREB3 CRKL CTXN3 CXCL16 CYB561 CYB5B ELOVL4 ERGIC3 EXOC3L2 FAM209A FAM241B FAM3C FATE1 FCGR1A GPX8 GRM2 INSIG2 KCNN4 MARCHF5 MCL1 MS4A13 NAT8 NR2F2 NRM PBX3 PGAP2 PGRMC1 PLN PLP1 PLP2 PLPP4 REEP4 RUSF1 S100A1 SCAMP4 SEC22A SELENOK SERP1 SERP2 SLC35E3 SLC37A4 SLC39A7 SMIM1 SOCS3 STRIT1 STX8 TANK TMBIM1 TMEM107 TMEM11 TMEM14B TMEM14C TMEM199 TMEM222 TMEM229B TMEM243 TMEM254 TMEM60 TMEM80 TMEM86B TMEM97 TRARG1 TSPO2 UBE2D1 UBIAD1 VAMP3 VAMP5 ZFPL1
Entrez ID		140456	638
HPRD ID		06450	04547
Ensembl ID		ENSG00000165192	ENSG00000100290
Uniprot IDs		Q7Z670 Q8WXH4	A0A024R4X6 Q13323
PDB IDs		4UUC	2IPE
Enriched GO Terms of Interacting Partners?
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