RALYL and AEBP2

Data Source:
HPRD (two hybrid)

		RALYL	AEBP2
Description		RALY RNA binding protein like	AE binding protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Chromatin Nucleoplasm ESC/E(Z) Complex
	Molecular Function	RNA Binding Protein Binding Identical Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Metal Ion Binding
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Gene Expression, Epigenetic
Pathways			PRC2 methylates histones and DNA PKMTs methylate histone lysines
Drugs
Diseases
GWAS		Adult body size ( 32376654) Body mass index ( 28892062 25673413) Depressive symptoms x independent stressful life events interaction (1df test) ( 30718454) Depressive symptoms x independent stressful life events interaction (2df test) ( 30718454) Diastolic blood pressure ( 27841878) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Night sleep phenotypes ( 27126917) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Systolic blood pressure ( 27841878) Trunk fat mass ( 28552196)	Body size at age 10 ( 32376654) Chronic mountain sickness ( 31417607) Diastolic blood pressure ( 30224653) Diverticular disease ( 30177863) Height ( 28552196) Lung function (FEV1/FVC) ( 30804560) Manganese levels ( 26025379) Obesity-related traits ( 23251661) Opioid use cessation ( 31936517) Pulmonary function ( 21946350) Response to fenofibrate (LDL cholesterol levels) ( 27002377)
Interacting Genes		22 interacting genes: AEBP2 AEN BYSL C20orf27 CAMK2A CCDC85B CEP170P1 EWSR1 FXR2 HNRNPC HNRNPCL1 HNRNPCL2 LMO3 LRRK2 MCRS1 PSMF1 RALY RBM41 THAP1 TIGD3 TSNAX ZNF408	18 interacting genes: APP EED H1-1 H1-2 HMBOX1 JMJD6 KRTAP10-8 LDOC1 MDFI PICK1 RALYL RBBP4 SUZ12 THAP1 TRIM55 TRIM63 TSPYL2 ZNF408
Entrez ID		138046	121536
HPRD ID		11236	16477
Ensembl ID		ENSG00000184672	ENSG00000139154
Uniprot IDs		B3KT61 Q86SE5	Q6ZN18
PDB IDs			5WAI 5Y0U 5Y1U 6C23 6C24
Enriched GO Terms of Interacting Partners?
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