GLYCTK and RBCK1

Data Source:
BioGRID (two hybrid)

		GLYCTK	RBCK1
Description		glycerate kinase	RANBP2-type and C3HC4-type zinc finger containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Golgi Apparatus Cytosol	Ubiquitin Ligase Complex Cytosol LUBAC Complex
	Molecular Function	Protein Binding ATP Binding Glycerate Kinase Activity	Ubiquitin-protein Transferase Activity Protein Binding Identical Protein Binding Ubiquitin Binding Metal Ion Binding
	Biological Process	Protein Phosphorylation Fructose Catabolic Process To Hydroxyacetone Phosphate And Glyceraldehyde-3-phosphate	Protein Polyubiquitination I-kappaB Kinase/NF-kappaB Signaling Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Viral Process Negative Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process T Cell Receptor Signaling Pathway Positive Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Necroptotic Process Protein Linear Polyubiquitination Positive Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		Fructose catabolism	Regulation of TNFR1 signaling TNFR1-induced NFkappaB signaling pathway Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972) Hemoglobin levels ( 32327693) Schizophrenia ( 28991256 23974872)	Night sleep phenotypes ( 27126917)
Interacting Genes		59 interacting genes: ADAMTSL4 ANKRD53 ARMC5 ATP23 BAIAP2L2 C19orf54 CALCOCO2 CEP70 DTX2 EFHC2 GMPPB GOLGA2 IHO1 KLHL12 KRT13 KRT15 KRT19 KRT34 KRT75 KRTAP19-5 KRTAP6-2 KRTAP6-3 LZTS2 MAGED1 METTL15 METTL27 MGAT5B MIS18A MORN3 NFKBID NOTO NT5C2 PFDN5 PICK1 PLAGL2 POMC PRDM14 PUDP RBCK1 RBPMS REL SAXO1 SERTAD1 SMUG1 SNF8 SPAG8 SPRED1 STK33 TRIM27 TRIM42 TRIP13 TUBGCP4 UBP1 UFSP1 ZFP90 ZG16 ZIM2 ZNF620 ZNF688	65 interacting genes: APP ARNT2 BACH1 CREB5 CREBBP ENKD1 GLYCTK HGS HOXA1 HOXC8 IL16 IREB2 KANK2 LNX1 MALT1 MAP3K1 MAPKBP1 MKRN2 NAA10 NDUFAF3 NEDD4 NR1I2 OTUB2 OTUD6A PAN2 PCGF2 PRKCA PRKN PSMA1 PSMD4 RNF181 RNF31 SMURF1 SOCS6 SYCE1 TNFAIP3 TP53 TRAF1 TRIM21 TRIM25 TRIM65 TRIML1 TSSK3 TTC23 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2G1 UBE2K UBE2L3 UBE2L6 UBE2N UBE2S UBE2U UCHL5 UHRF2 USP15 USP2 USP21 USP32 USP49 USP7 ZNF414
Entrez ID		132158	10616
HPRD ID		13586	16643
Ensembl ID		ENSG00000168237	ENSG00000125826
Uniprot IDs		A1LQE8 Q8IVS8	A6PVJ6 A6PVK0 Q9BYM8
PDB IDs			2CRC 2LGY 4DBG
Enriched GO Terms of Interacting Partners?
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