MISP and PPP1R16B

Data Source:
BioGRID (two hybrid)

		MISP	PPP1R16B
Description		mitotic spindle positioning	protein phosphatase 1 regulatory subunit 16B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Actin Filament Plasma Membrane Focal Adhesion Cortical Actin Cytoskeleton Spindle Pole Centrosome Intracellular Membrane-bounded Organelle Mitotic Spindle Astral Microtubule End	Nucleus Plasma Membrane Nuclear Speck Cell Projection Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Actin Filament Binding	Protein Binding Protein Phosphatase 1 Binding Myosin Phosphatase Regulator Activity Protein Phosphatase Regulator Activity
	Biological Process	Establishment Of Mitotic Spindle Orientation Cell Migration Cell Division Organelle Localization Establishment Of Centrosome Localization Mitotic Spindle Assembly Regulation Of Protein Localization To Cell Cortex	Positive Regulation Of Endothelial Cell Proliferation Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Protein Dephosphorylation Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Protein Dephosphorylation Regulation Of Phosphoprotein Phosphatase Activity Regulation Of Filopodium Assembly Establishment Of Endothelial Barrier Negative Regulation Of Peptidyl-serine Dephosphorylation Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Regulation Of Sprouting Angiogenesis
Pathways
Drugs
Diseases
GWAS			Alcohol dependence or chronic alcoholic pancreatitis or alcohol-related liver cirrhosis ( 28714907) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Diverticular disease ( 30177863) Huntington's disease progression ( 28642124) Mean corpuscular volume ( 32888494) Platelet distribution width ( 32888494) Schizophrenia ( 25056061 29483656 30285260)
Interacting Genes		49 interacting genes: BHLHB9 BLZF1 C19orf54 CCDC33 CDPF1 CEP76 CRBN DPH2 DPPA4 EFHC2 ENKD1 EZR FHL2 FHL5 GOLGA2 HNRNPK HSF2BP HSPB2 HSPB2-C11orf52 HSPB8 IKZF3 IRAK1BP1 KRTAP12-3 LMO1 LMO2 MAP1LC3C MORN3 MORN5 OIP5 PAX6 PFDN5 PIH1D1 PIH1D2 PNMA2 PPP1R16B PRR5L RIBC1 RINT1 RUSC1 SNW1 SOCS7 SPATC1L SPATS1 TERF1 TRAF2 TRIB3 TRIP6 VBP1 ZNF620	37 interacting genes: ATPAF2 CDCA7L CEP55 CEP70 CRX DVL2 DVL3 FAM83A FARS2 FLYWCH1 GATA1 GFAP GOLGA2 HAPLN2 IKZF3 KCTD9 MAGOH MISP NEFL PATZ1 PHC2 PLEKHN1 PPP1CA PPP1CB RBPMS RFC5 SCNM1 SF3B4 SHC3 TACO1 TADA2A TASOR2 TFIP11 TLE5 TXN2 ZNF410 ZNF564
Entrez ID		126353	26051
HPRD ID		12695	15168
Ensembl ID		ENSG00000099812	ENSG00000101445
Uniprot IDs		Q8IVT2	Q96T49
PDB IDs
Enriched GO Terms of Interacting Partners?
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