PPP1R16B and MAGOH

Data Source:
BioGRID (two hybrid)

		PPP1R16B	MAGOH
Description		protein phosphatase 1 regulatory subunit 16B	mago homolog, exon junction complex subunit
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Plasma Membrane Nuclear Speck Cell Projection Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm Cytoplasm Nuclear Speck Exon-exon Junction Complex Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding Protein Phosphatase 1 Binding Myosin Phosphatase Regulator Activity Protein Phosphatase Regulator Activity	RNA Binding Protein Binding
	Biological Process	Positive Regulation Of Endothelial Cell Proliferation Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Protein Dephosphorylation Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Protein Dephosphorylation Regulation Of Phosphoprotein Phosphatase Activity Regulation Of Filopodium Assembly Establishment Of Endothelial Barrier Negative Regulation Of Peptidyl-serine Dephosphorylation Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Regulation Of Sprouting Angiogenesis	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome RNA Export From Nucleus MRNA Export From Nucleus Regulation Of Translation RNA Splicing MRNA 3'-end Processing
Pathways			Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Alcohol dependence or chronic alcoholic pancreatitis or alcohol-related liver cirrhosis ( 28714907) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Diverticular disease ( 30177863) Huntington's disease progression ( 28642124) Mean corpuscular volume ( 32888494) Platelet distribution width ( 32888494) Schizophrenia ( 25056061 29483656 30285260)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		37 interacting genes: ATPAF2 CDCA7L CEP55 CEP70 CRX DVL2 DVL3 FAM83A FARS2 FLYWCH1 GATA1 GFAP GOLGA2 HAPLN2 IKZF3 KCTD9 MAGOH MISP NEFL PATZ1 PHC2 PLEKHN1 PPP1CA PPP1CB RBPMS RFC5 SCNM1 SF3B4 SHC3 TACO1 TADA2A TASOR2 TFIP11 TLE5 TXN2 ZNF410 ZNF564	19 interacting genes: ALYREF CEP70 CORO1A DPH2 DPPA4 EIF4A3 FXR1 GOLGA2 IPO13 MAP1B NXF1 PPP1R16B RBM8A TADA2A UPF3B XIST YWHAQ ZKSCAN8 ZRANB1
Entrez ID		26051	4116
HPRD ID		15168	04005
Ensembl ID		ENSG00000101445	ENSG00000162385
Uniprot IDs		Q96T49	P61326
PDB IDs			1P27 2HYI 2J0Q 2J0S 2XB2 3EX7 7A5P
Enriched GO Terms of Interacting Partners?
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