ZNF441 and PCSK6

Data Source:
BioGRID (two hybrid)

		ZNF441	PCSK6
Description		zinc finger protein 441	proprotein convertase subtilisin/kexin type 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Extracellular Region Extracellular Space Endoplasmic Reticulum Golgi Lumen Plasma Membrane Cell Surface Membrane Collagen-containing Extracellular Matrix
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding	Endopeptidase Activity Serine-type Endopeptidase Activity Protein Binding Heparin Binding Nerve Growth Factor Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Glycoprotein Metabolic Process Protein Processing Peptide Hormone Processing Regulation Of BMP Signaling Pathway Nerve Growth Factor Processing Nerve Growth Factor Production Secretion By Cell Regulation Of Lipoprotein Lipase Activity Cornification
Pathways		Generic Transcription Pathway	Signaling by NODAL NGF processing Formation of the cornified envelope Assembly of active LPL and LIPC lipase complexes
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Metabolite levels ( 23823483)	Apolipoprotein A1 levels ( 32203549) Apolipoprotein B levels ( 32203549) Cytokine levels ( 31679650) Cytokine network levels (multivariate analysis) ( 31679650) Handedness in dyslexia ( 21051773) Height ( 31562340) Inflammatory biomarkers (multivariate analysis) ( 33110245) Platelet-derived growth factor BB levels ( 27989323) Red blood cell count ( 32888494) Relative hand skill in reading disability ( 24068947) Triglyceride levels ( 32203549) Triglycerides ( 30275531) Tuberculosis ( 30713548) Type 2 diabetes ( 30470734)
Interacting Genes		8 interacting genes: CYSRT1 DVL3 MDFI PCSK6 SPRY1 STX1A TEX48 YPEL3	6 interacting genes: CACNA1A FLG PCSK5 PMCH RCN3 ZNF441
Entrez ID		126068	5046
HPRD ID		15794	01329
Ensembl ID		ENSG00000197044	ENSG00000140479
Uniprot IDs		Q8N8Z8	A2RQD9 H7BXT3 P29122 Q59H04
PDB IDs
Enriched GO Terms of Interacting Partners?
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