TRAPPC5 and HMG20A

Data Source:
BioGRID (two hybrid)

		TRAPPC5	HMG20A
Description		trafficking protein particle complex subunit 5	high mobility group 20A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Cytosol TRAPP Complex TRAPPI Protein Complex TRAPPII Protein Complex TRAPPIII Protein Complex	Nucleus
	Molecular Function	Protein Binding	DNA Binding Protein Binding Identical Protein Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport COPII Vesicle Coating	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Negative Regulation Of Protein Sumoylation Negative Regulation Of Neuron Differentiation
Pathways		COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs
Drugs		S-palmitoyl-L-cysteine
Diseases
GWAS			Hand grip strength ( 29691431) Hemoglobin A1c levels ( 29403010) Medication use (drugs used in diabetes) ( 31015401) Type 2 diabetes ( 21490949 22885922 24509480 30054458 22693455 21874001 30297969 32499647 30718926 28869590)
Interacting Genes		7 interacting genes: A2M CCNDBP1 HMG20A TRAPPC2 TRAPPC2B TRAPPC3 TRAPPC3L	58 interacting genes: ADD1 AGR2 BACH2 BRAP C9orf72 CCDC136 CCNK CEP95 CFAP53 DCTN4 DDIT4L DGCR6L DTNA DTNB FBXO7 FMNL1 FOXD4L1 GADD45GIP1 GPSM1 GTF2A1L HMG20B HPCAL1 KIFC3 KPNA2 KRT1 LMO1 LNX1 LURAP1 MAGOHB NTAQ1 NUTF2 OLIG3 PHF21A PIAS2 PICK1 PSMB1 PSORS1C2 PSTPIP1 PTH2R QARS1 RAD54L2 RBM7 RIN1 RPP30 RPRD1B RSPH9 RUSC1 SCNM1 SMAD4 SMYD1 SUOX SYTL4 TBC1D22B TCP11L1 TESC TRAF4 TRAPPC5 USHBP1
Entrez ID		126003	10363
HPRD ID		15547	16116
Ensembl ID		ENSG00000181029	ENSG00000140382
Uniprot IDs		Q8IUR0	B4DMG1 Q9NP66
PDB IDs
Enriched GO Terms of Interacting Partners?
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