HMG20A and CFAP53

Data Source:
BioGRID (two hybrid)

		HMG20A	CFAP53
Description		high mobility group 20A	cilia and flagella associated protein 53
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Cellular_component Extracellular Region Cilium
	Molecular Function	DNA Binding Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Negative Regulation Of Protein Sumoylation Negative Regulation Of Neuron Differentiation	Cilium Movement Determination Of Left/right Symmetry Cilium Assembly Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry
Pathways
Drugs
Diseases
GWAS		Hand grip strength ( 29691431) Hemoglobin A1c levels ( 29403010) Medication use (drugs used in diabetes) ( 31015401) Type 2 diabetes ( 21490949 22885922 24509480 30054458 22693455 21874001 30297969 32499647 30718926 28869590)
Interacting Genes		58 interacting genes: ADD1 AGR2 BACH2 BRAP C9orf72 CCDC136 CCNK CEP95 CFAP53 DCTN4 DDIT4L DGCR6L DTNA DTNB FBXO7 FMNL1 FOXD4L1 GADD45GIP1 GPSM1 GTF2A1L HMG20B HPCAL1 KIFC3 KPNA2 KRT1 LMO1 LNX1 LURAP1 MAGOHB NTAQ1 NUTF2 OLIG3 PHF21A PIAS2 PICK1 PSMB1 PSORS1C2 PSTPIP1 PTH2R QARS1 RAD54L2 RBM7 RIN1 RPP30 RPRD1B RSPH9 RUSC1 SCNM1 SMAD4 SMYD1 SUOX SYTL4 TBC1D22B TCP11L1 TESC TRAF4 TRAPPC5 USHBP1	29 interacting genes: APP CBY1 CCDC57 CCDC85B CCHCR1 CCNC CEP70 CWF19L2 GAS8 GRIPAP1 HIP1 HMG20A KRT31 KRT34 LDOC1 LENG8 MYOG PARVG PIBF1 PNMA1 RABEP1 SH2D4A TBC1D21 TEX11 TNIP1 TRIM23 TRIM54 TXLNA TXLNB
Entrez ID		10363	220136
HPRD ID		16116	09958
Ensembl ID		ENSG00000140382	ENSG00000172361
Uniprot IDs		B4DMG1 Q9NP66	Q96M91
PDB IDs
Enriched GO Terms of Interacting Partners?
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