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MICOS13 and DIABLO
Data Source:
BioGRID
(two hybrid)
MICOS13
DIABLO
Description
mitochondrial contact site and cristae organizing system subunit 13
diablo IAP-binding mitochondrial protein
Image
No pdb structure
GO Annotations
Cellular Component
SAM Complex
Nucleoplasm
Mitochondrion
Mitochondrial Inner Membrane
Mitochondrial Crista Junction
MICOS Complex
MIB Complex
Mitochondrion
Mitochondrial Intermembrane Space
Cytosol
Cytoplasmic Side Of Plasma Membrane
CD40 Receptor Complex
Molecular Function
Protein Binding
Protein Binding
Biological Process
Inner Mitochondrial Membrane Organization
Cristae Formation
Apoptotic Process
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C
Positive Regulation Of Apoptotic Process
Neuron Apoptotic Process
Intrinsic Apoptotic Signaling Pathway
Pathways
Cristae formation
Release of apoptotic factors from the mitochondria
SMAC (DIABLO) binds to IAPs
SMAC (DIABLO) binds to IAPs
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes
SMAC, XIAP-regulated apoptotic response
Regulation of the apoptosome activity
Drugs
Phenethyl Isothiocyanate
Diseases
GWAS
Interacting Genes
10 interacting genes:
ACSF2
APOC1
APOC2
APOC4
DIABLO
HSFX1
HSFX2
PBX3
RHBDD2
TEX44
42 interacting genes:
AGTRAP
APOC2
APOC4
AREL1
ARL6IP1
ARNT
BEX3
BIRC2
BIRC3
BIRC5
BIRC6
BIRC7
CASP9
CMTM4
DERL2
DGAT2L6
DHRS1
E2F1
EEF1A1
FADS6
FKBP7
HSD17B13
HTRA2
LTBR
MAML2
MICOS13
MPC2
NR4A1
RHBDD2
RMDN2
SEC22A
SFT2D1
SLC17A9
SLC25A47
SLC66A2
STMN4
SYP
TIMMDC1
UBE2K
UFM1
XIAP
ZNF746
Entrez ID
125988
56616
HPRD ID
15198
05560
Ensembl ID
ENSG00000174917
ENSG00000184047
Uniprot IDs
A0A140TA84
A0A140TA86
Q5XKP0
A0A024RBT2
A0A0S2Z5P6
A0A0S2Z5U7
K7X1S0
Q502X2
Q9NR28
PDB IDs
1FEW
1G3F
1G73
1OXQ
1TW6
1XB0
1XB1
3D9U
3UIH
3UIJ
4TX5
6JX6
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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