MSI2 and DYNLL2

Data Source:
BioGRID (affinity chromatography technology)

		MSI2	DYNLL2
Description		musashi RNA binding protein 2	dynein light chain LC8-type 2
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GO Annotations	Cellular Component	Cytoplasm Cytosol Polysome Intracellular Membrane-bounded Organelle	Nucleus Centrosome Cytosol Cytoplasmic Dynein Complex Microtubule Plasma Membrane Cilium Postsynaptic Density Membrane Dynein Complex Myosin V Complex Ciliary Tip 9+0 Non-motile Cilium Postsynapse Glutamatergic Synapse
	Molecular Function	RNA Binding Protein Binding Identical Protein Binding	Motor Activity Protein Binding Identical Protein Binding Protein-containing Complex Binding Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding Scaffold Protein Binding
	Biological Process		Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Macroautophagy Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Intraciliary Transport Involved In Cilium Assembly Cilium Assembly Positive Regulation Of ATP-dependent Microtubule Motor Activity, Plus-end-directed
Pathways			Activation of BMF and translocation to mitochondria Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Macroautophagy MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) Intraflagellar transport RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase HCMV Early Events Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Birth weight ( 31043758) Chronotype ( 30696823) Coronary artery calcification ( 23870195) Decreased low contrast letter acuity in multiple sclerosis ( 31289819) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Freckles ( 29895819) Height ( 31562340) Male-pattern baldness ( 29146897 27182965) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean platelet volume ( 32888494 27863252) Metabolite levels ( 23823483) Neutrophil count ( 32888494) Peginterferon alfa-2a treatment response in chronic hepatitis B infection ( 30972912) Platelet count ( 32888494) Plateletcrit ( 32888494 27863252) Pulse pressure ( 30224653) Rapid automised naming of pictures ( 30741946) Refractive error ( 32231278) Schizophrenia ( 28991256 30285260) White blood cell count ( 32888494)	Blood protein levels ( 30072576)
Interacting Genes		66 interacting genes: GRB2 HNRNPH1 HNRNPH2 MEOX2 MIR1-1 MIR106A MIR106B MIR10B MIR128-1 MIR128-2 MIR138-2 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29B1 MIR29B2 MIR29C MIR34A MIR34B MIR34C MIR363 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I	35 interacting genes: BCL2L11 BMF C12orf40 C14orf119 DLGAP1 DNAL4 DPPA3 DYNC1I1 EWSR1 FAM117B GABARAPL2 GPHN GPRIN2 HDAC6 HMBOX1 HOMER3 IHO1 KANK2 MEOX2 MORN3 MYO5A OTUD6A PAK1 PKIA PKIG RASGRP3 SECISBP2L SKAP1 SMCP SPAG8 THAP10 TLK1 TPPP XIAP ZAR1
Entrez ID		124540	140735
HPRD ID		07438	06489
Ensembl ID		ENSG00000153944	ENSG00000264364
Uniprot IDs		B4DHE8 Q96DH6	Q96FJ2
PDB IDs		6C8U 6DBP 6NTY	2XQQ 3P8M 4D07
Enriched GO Terms of Interacting Partners?
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