ZNF641 and SQLE

Data Source:
BioGRID (two hybrid)

		ZNF641	SQLE
Description		zinc finger protein 641	squalene epoxidase
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Metal Ion Binding	Squalene Monooxygenase Activity Protein Binding FAD Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Cholesterol Biosynthetic Process Cellular Aromatic Compound Metabolic Process Cholesterol Metabolic Process Response To Organic Substance Sterol Biosynthetic Process Regulation Of Cell Population Proliferation Regulation Of Cholesterol Biosynthetic Process Lipid Droplet Formation
Pathways		Generic Transcription Pathway	Cholesterol biosynthesis Activation of gene expression by SREBF (SREBP)
Drugs			Naftifine Terbinafine Butenafine Ellagic acid
Diseases
GWAS		Estimated glomerular filtration rate ( 31152163 31015462) Hematocrit ( 27863252) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Obstructive sleep apnea trait (apnea hypopnea index) ( 29077507) Red blood cell count ( 27863252)	Amyotrophic lateral sclerosis ( 24931836) Amyotrophic lateral sclerosis or frontotemporal dementia ( 24931836) Metabolite levels ( 23823483)
Interacting Genes		8 interacting genes: APP DTX2 KDM1A LMO1 LMO2 LMO3 SCNM1 SQLE	6 interacting genes: ALDOC CREB3 CREB3L1 REEP4 TMEM14B ZNF641
Entrez ID		121274	6713
HPRD ID		08711	11802
Ensembl ID		ENSG00000167528	ENSG00000104549
Uniprot IDs		Q96N77	Q14534 Q5HYI4
PDB IDs			6C6N 6C6P 6C6R
Enriched GO Terms of Interacting Partners?
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