SQLE and ALDOC

Data Source:
BioGRID (two hybrid)

		SQLE	ALDOC
Description		squalene epoxidase	aldolase, fructose-bisphosphate C
Image
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle	Extracellular Region Cytosol Cytoskeleton Secretory Granule Lumen Extracellular Exosome Tertiary Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	Squalene Monooxygenase Activity Protein Binding FAD Binding	Fructose-bisphosphate Aldolase Activity Protein Binding Cytoskeletal Protein Binding
	Biological Process	Cholesterol Biosynthetic Process Cellular Aromatic Compound Metabolic Process Cholesterol Metabolic Process Response To Organic Substance Sterol Biosynthetic Process Regulation Of Cell Population Proliferation Regulation Of Cholesterol Biosynthetic Process Lipid Droplet Formation	Fructose Metabolic Process Gluconeogenesis Glycolytic Process Fructose 1,6-bisphosphate Metabolic Process Epithelial Cell Differentiation Neutrophil Degranulation Canonical Glycolysis
Pathways		Cholesterol biosynthesis Activation of gene expression by SREBF (SREBP)	Neutrophil degranulation Glycolysis Gluconeogenesis
Drugs		Naftifine Terbinafine Butenafine Ellagic acid
Diseases
GWAS		Amyotrophic lateral sclerosis ( 24931836) Amyotrophic lateral sclerosis or frontotemporal dementia ( 24931836) Metabolite levels ( 23823483)
Interacting Genes		6 interacting genes: ALDOC CREB3 CREB3L1 REEP4 TMEM14B ZNF641	7 interacting genes: ANKS1A ATP6V1E1 ERBB2 LNX1 MAP2K3 PLD2 SQLE
Entrez ID		6713	230
HPRD ID		11802	02386
Ensembl ID		ENSG00000104549	ENSG00000109107
Uniprot IDs		Q14534 Q5HYI4	A0A024QZ64 P09972
PDB IDs		6C6N 6C6P 6C6R	1XFB
Enriched GO Terms of Interacting Partners?
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