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CLTB and HIP1R
Data Source:
HPRD
(in vitro, two hybrid)
CLTB
HIP1R
Description
clathrin light chain B
huntingtin interacting protein 1 related
Image
No pdb structure
GO Annotations
Cellular Component
Trans-Golgi Network
Cytosol
Plasma Membrane
Clathrin Coat
Clathrin Vesicle Coat
Clathrin Coat Of Trans-Golgi Network Vesicle
Clathrin Coat Of Coated Pit
Synaptic Vesicle Membrane
Intracellular Membrane-bounded Organelle
Clathrin-coated Endocytic Vesicle
Ciliary Membrane
Presynaptic Endocytic Zone Membrane
Postsynaptic Endocytic Zone Cytoplasmic Component
Mitochondrion
Cytosol
Cytoskeleton
Plasma Membrane
Clathrin-coated Pit
Cell Cortex
Postsynaptic Density
Apical Plasma Membrane
Clathrin-coated Vesicle
Clathrin-coated Vesicle Membrane
Ruffle Membrane
Dendrite Cytoplasm
Neuronal Cell Body
Dendritic Spine
Intracellular Membrane-bounded Organelle
Perinuclear Region Of Cytoplasm
Synaptic Membrane
Molecular Function
Structural Molecule Activity
Protein Binding
Clathrin Heavy Chain Binding
Peptide Binding
Protein Binding
Phosphatidylinositol-4,5-bisphosphate Binding
Phosphatidylinositol-3,4,5-trisphosphate Binding
SH3 Domain Binding
Clathrin Binding
Clathrin Light Chain Binding
Phosphatidylinositol Binding
Clathrin Adaptor Activity
Identical Protein Binding
Protein Homodimerization Activity
Phosphatidylinositol-3,4-bisphosphate Binding
Protein Heterodimerization Activity
Actin Filament Binding
Phosphatidylinositol-3,5-bisphosphate Binding
Biological Process
Intracellular Protein Transport
Clathrin Coat Assembly
Membrane Organization
Clathrin-dependent Endocytosis
Endocytosis
Receptor-mediated Endocytosis
Apoptotic Process
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Actin Filament Organization
Regulation Of Endocytosis
Negative Regulation Of Actin Filament Polymerization
Positive Regulation Of Protein Binding
Regulation Of Actin Cytoskeleton Organization
Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Positive Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Clathrin Coat Assembly
Protein Stabilization
Digestive System Development
Regulation Of Gastric Acid Secretion
Membrane Organization
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Positive Regulation Of Clathrin Coat Assembly
Regulation Of Clathrin-dependent Endocytosis
Positive Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway
Pathways
Gap junction degradation
Formation of annular gap junctions
EPH-ephrin mediated repulsion of cells
Lysosome Vesicle Biogenesis
WNT5A-dependent internalization of FZD4
WNT5A-dependent internalization of FZD2, FZD5 and ROR2
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
Golgi Associated Vesicle Biogenesis
Clathrin-mediated endocytosis
Drugs
Diseases
GWAS
Obesity-related traits (
23251661
)
Atrial fibrillation (
30061737
29892015
)
Body mass index (
29273807
)
Mean platelet volume (
32888494
)
Parkinson's disease (
21292315
)
Parkinson's disease or first degree relation to individual with Parkinson's disease (
31701892
)
Schizophrenia (
30285260
)
Tourette syndrome (
30818990
)
Interacting Genes
9 interacting genes:
CALM1
CLTC
CSNK2A1
CSNK2A2
HIP1
HIP1R
HTR4
MYO6
PQBP1
13 interacting genes:
ACTA1
ACTB
CLTA
CLTB
CLTC
CTTN
DYNLL1
EPN1
HIP1
HTT
NDC80
TFIP11
TRIM27
Entrez ID
1212
9026
HPRD ID
00352
10412
Ensembl ID
ENSG00000175416
ENSG00000130787
Uniprot IDs
A0A024R7S3
P09497
B3KQW8
B4DPL0
O75146
PDB IDs
1R0D
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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