CLPTM1 and CCR2

  • Data Source:
  • BioGRID (two hybrid)

CLPTM1

CCR2

Description CLPTM1 regulator of GABA type A receptor forward trafficking C-C motif chemokine receptor 2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease or family history of Alzheimer's disease ( 30617256)
  • Alzheimer's disease or HDL levels (pleiotropy) ( 30805717)
  • Apolipoprotein B levels ( 32203549)
  • Basal cell carcinoma ( 31174203)
  • Body mass index ( 26426971)
  • Body mass index (age>50) ( 26426971)
  • Body mass index x age interaction ( 26426971)
  • Body mass index x sex x age interaction (4df test) ( 26426971)
  • Carotid intima media thickness (maximum) ( 31801372)
  • Carotid intima media thickness (mean) ( 31801372)
  • Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321)
  • Cerebrospinal AB1-42 levels in mild cognitive impairment ( 29274321)
  • Cerebrospinal AB1-42 levels in normal cognition ( 29274321)
  • Cerebrospinal fluid AB1-42 levels ( 29274321)
  • Cerebrospinal fluid p-tau levels ( 29274321)
  • Cerebrospinal fluid p-tau levels in mild cognitive impairment ( 29274321)
  • Cerebrospinal fluid t-tau levels ( 29274321)
  • Cerebrospinal fluid t-tau levels in mild cognitive impairment ( 29274321)
  • Hippocampal volume ( 29274321)
  • Hippocampal volume in Alzheimer's disease dementia ( 29274321)
  • Keratinocyte cancer (MTAG) ( 31174203)
  • LDL cholesterol levels ( 32203549)
  • Logical memory (delayed recall) ( 29274321)
  • Logical memory (immediate recall) ( 29274321)
  • Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)
Interacting Genes 8 interacting genes: CCR2 CCR4 F2RL1 FZD7 LINC00839 SLC22A1 SLC22A2 UNC93B1 40 interacting genes: APP ARL6IP5 ATP2B1 B3GAT3 BLOC1S6 CACYBP CD59 CD81 CDIP1 CLPTM1 DMWD EMC10 ERGIC3 GOT1 GPR161 HERPUD1 HMOX2 JPH3 NDFIP1 NOTCH2 NTNG2 PCMT1 PLLP PTPN9 RGR RHOG RTN3 S1PR5 SCG5 SLC2A1 SLC41A3 SRSF5 SUMO1 SVOP TECPR2 TMEM161A TMEM199 TMEM63A TSPAN7 WLS
Entrez ID 1209 729230
HPRD ID 07544 19667
Ensembl ID ENSG00000104853 ENSG00000121807
Uniprot IDs A0A0S2Z3H2 O96005 A0A024R2Q0 P41597
PDB IDs 1KAD 1KP1 2MLO 2MLQ 5T1A
Enriched GO Terms of Interacting Partners?
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