DEFB118 and GUCA1A

Data Source:
BioGRID (two hybrid)

		DEFB118	GUCA1A
Description		defensin beta 118	guanylate cyclase activator 1A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region	Photoreceptor Inner Segment Photoreceptor Disc Membrane Cone Photoreceptor Outer Segment
	Molecular Function	Protein Binding	Calcium Ion Binding Protein Binding Calcium Sensitive Guanylate Cyclase Activator Activity Guanylate Cyclase Regulator Activity
	Biological Process	Cell-matrix Adhesion Spermatogenesis Killing Of Cells Of Other Organism Defense Response To Bacterium Innate Immune Response Defense Response To Gram-negative Bacterium Membrane Disruption In Other Organism Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide	Signal Transduction Visual Perception Phototransduction Positive Regulation Of CGMP-mediated Signaling Regulation Of Rhodopsin Mediated Signaling Pathway Positive Regulation Of Guanylate Cyclase Activity Cellular Response To Calcium Ion
Pathways		Beta defensins Defensins	Inactivation, recovery and regulation of the phototransduction cascade
Drugs			Myristic acid
Diseases			Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD)
GWAS		Prudent dietary pattern ( 28644415) TPE interval (resting) ( 32386560)	Spatial processing ( 31596458)
Interacting Genes		1 interacting genes: GUCA1A	9 interacting genes: AGR2 C1QTNF5 DDIT4L DEFB118 GSC2 GUCY2D HSPB1 KATNAL1 PRKAR1B
Entrez ID		117285	2978
HPRD ID		09629	02648
Ensembl ID		ENSG00000131068	ENSG00000048545
Uniprot IDs		A0A384MTK2 Q96PH6	B2R9P6 P43080
PDB IDs
Enriched GO Terms of Interacting Partners?
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