AGAP1 and ALPI

Data Source:
HPRD (in vivo, in vitro)

		AGAP1	ALPI
Description		ArfGAP with GTPase domain, ankyrin repeat and PH domain 1	alkaline phosphatase, intestinal
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Extracellular Region Plasma Membrane Anchored Component Of Membrane
	Molecular Function	GTPase Activity GTPase Activator Activity Protein Binding GTP Binding Phospholipid Binding Metal Ion Binding	Magnesium Ion Binding Protease Binding Alkaline Phosphatase Activity Protein Binding Zinc Ion Binding
	Biological Process	Protein Transport Positive Regulation Of GTPase Activity	Phosphatidic Acid Biosynthetic Process Digestion Dephosphorylation
Pathways			Synthesis of PA Post-translational modification: synthesis of GPI-anchored proteins Digestion
Drugs
Diseases
GWAS		Adult body size ( 32376654) Aspartate aminotransferase levels in non-alcoholic fatty liver disease ( 31311600) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Craniofacial microsomia ( 26853712) Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010) Menarche (age at onset) ( 23667675) Venlafaxine response in generalised anxiety disorder (responders vs non-responders after 24 weeks) ( 28437668)	Hepcidin/ferritin ratio ( 27846281) Refractive error ( 32231278)
Interacting Genes		14 interacting genes: APP ARF1 ARF6 CDC42 GRB7 GUCY1A1 GUCY1B1 RAC1 RHOA RSPH14 SMN1 SRC TK1 ZNF534	8 interacting genes: BICD1 HSPB1 IRF5 KRTAP10-3 KRTAP10-8 KRTAP10-9 NOD2 NOTCH2NLA
Entrez ID		116987	248
HPRD ID		16359	01376
Ensembl ID		ENSG00000157985	ENSG00000163295
Uniprot IDs		B2RZG9 Q9UPQ3 X5D293	A0A024R4A2 P09923
PDB IDs
Enriched GO Terms of Interacting Partners?
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