RASGRP4 and TMPRSS4

Data Source:
BioGRID (two hybrid)

		RASGRP4	TMPRSS4
Description		RAS guanyl releasing protein 4	transmembrane serine protease 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane Membrane	Extracellular Space Plasma Membrane Integral Component Of Membrane Secretory Granule
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Calcium Ion Binding Diacylglycerol Binding GTP-dependent Protein Binding	Serine-type Endopeptidase Activity Scavenger Receptor Activity Protein Binding Serine-type Peptidase Activity
	Biological Process	MAPK Cascade Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Activation Of Phospholipase C Activity Small GTPase Mediated Signal Transduction Regulation Of G Protein-coupled Receptor Signaling Pathway Cell Population Proliferation Response To Extracellular Stimulus Myeloid Cell Differentiation Positive Regulation Of Ras Protein Signal Transduction	Proteolysis Endocytosis Response To Wounding Regulation Of Gene Expression Protein Processing Negative Regulation Of Growth Rate Positive Regulation Of Viral Entry Into Host Cell
Pathways		FCERI mediated NF-kB activation RAF/MAP kinase cascade
Drugs
Diseases
GWAS		Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Diisocyanate-induced asthma ( 25918132) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Neutrophil percentage of granulocytes ( 27863252) Sum eosinophil basophil counts ( 27863252)
Interacting Genes		6 interacting genes: BNIP2 DYNLL1 HRAS RAP1A SEC22A TMPRSS4	14 interacting genes: BNIP3L CLEC7A CLRN1 ERVFRD-1 FAM209A FNDC9 GPX8 KASH5 LMNA RASGRP4 SIGLEC12 SUSD3 SYNE4 TMEM79
Entrez ID		115727	56649
HPRD ID		09540	05952
Ensembl ID		ENSG00000171777	ENSG00000137648
Uniprot IDs		Q8TDF6	B7Z458 B7Z8X1 B7Z900 Q9NRS4
PDB IDs		6AXG
Enriched GO Terms of Interacting Partners?
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