ZNF618 and G3BP2

Data Source:
BioGRID (two hybrid)

		ZNF618	G3BP2
Description		zinc finger protein 618	G3BP stress granule assembly factor 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Pericentric Heterochromatin	Cytoplasm Cytosol Cytoplasmic Stress Granule Ribonucleoprotein Complex
	Molecular Function	DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Identical Protein Binding Metal Ion Binding	RNA Binding MRNA Binding Protein Binding Signaling Receptor Complex Adaptor Activity
	Biological Process	Regulation Of Transcription, DNA-templated Positive Regulation Of Chromatin Binding	Cytoplasmic Sequestering Of NF-kappaB Ras Protein Signal Transduction Viral Process Stress Granule Assembly Innate Immune Response MRNA Transport Protein Homooligomerization Positive Regulation Of Stress Granule Assembly
Pathways
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Chronotype ( 30696823) Coronary artery aneurysm in Kawasaki disease ( 27171184) General risk tolerance (MTAG) ( 30643258) Low density lipoprotein cholesterol levels ( 30498476) Neutrophil level response to clozapine in treatment-resistant schizophrenia ( 30647433) Pulse pressure ( 30224653 30578418) Serum metabolite concentrations in chronic kidney disease ( 29545352) Systolic blood pressure ( 30578418) Tea consumption ( 31046077)	HDL cholesterol levels ( 32203549) Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261) Subjective response to lithium treatment in bipolar disorder ( 26503763) Testicular germ cell tumor ( 28604728)
Interacting Genes		12 interacting genes: CSNK1D CSNK1E DPPA3 G3BP2 MID1 NTAQ1 RIIAD1 TBC1D13 TPTEP2-CSNK1E UBE2I UBL5 UHRF2	60 interacting genes: MDM2 MIR1-1 MIR106A MIR106B MIR107 MIR10B MIR128-1 MIR128-2 MIR138-2 MIR140 MIR141 MIR145 MIR155 MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR19A MIR19B1 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29B1 MIR29C MIR31 MIR34A MIR34B MIR363 MIR429 MIR7-1 MIR7-2 MIR7-3 MIR92A1 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I NFKB1 NFKBIA PIN1 USP10 ZNF618
Entrez ID		114991	9908
HPRD ID		18719	06570
Ensembl ID		ENSG00000157657	ENSG00000138757
Uniprot IDs		Q5T7W0	A0A024RDB2 A0A024RDE5 Q9UN86
PDB IDs			5DRV
Enriched GO Terms of Interacting Partners?
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