ZNF618 and TPTEP2-CSNK1E

Data Source:
BioGRID (two hybrid)

		ZNF618	TPTEP2-CSNK1E
Description		zinc finger protein 618	TPTEP2-CSNK1E readthrough
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Pericentric Heterochromatin
	Molecular Function	DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription, DNA-templated Positive Regulation Of Chromatin Binding
Pathways			WNT mediated activation of DVL Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Circadian Clock Anchoring of the basal body to the plasma membrane Major pathway of rRNA processing in the nucleolus and cytosol AURKA Activation by TPX2
Drugs			Seliciclib
Diseases
GWAS		Adventurousness ( 30643258) Chronotype ( 30696823) Coronary artery aneurysm in Kawasaki disease ( 27171184) General risk tolerance (MTAG) ( 30643258) Low density lipoprotein cholesterol levels ( 30498476) Neutrophil level response to clozapine in treatment-resistant schizophrenia ( 30647433) Pulse pressure ( 30224653 30578418) Serum metabolite concentrations in chronic kidney disease ( 29545352) Systolic blood pressure ( 30578418) Tea consumption ( 31046077)
Interacting Genes		12 interacting genes: CSNK1D CSNK1E DPPA3 G3BP2 MID1 NTAQ1 RIIAD1 TBC1D13 TPTEP2-CSNK1E UBE2I UBL5 UHRF2	4 interacting genes: DVL3 PER2 TRIM3 ZNF618
Entrez ID		114991	102800317
HPRD ID		18719
Ensembl ID		ENSG00000157657	ENSG00000283900
Uniprot IDs		Q5T7W0	B3KRV2 P49674 Q5U045
PDB IDs			4HNI 4HOK
Enriched GO Terms of Interacting Partners?
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