UCN3 and IL10RB

Data Source:
HPRD (in vitro)

		UCN3	IL10RB
Description		urocortin 3	interleukin 10 receptor subunit beta
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Varicosity Axon Terminus	Plasma Membrane Integral Component Of Membrane Interleukin-28 Receptor Complex
	Molecular Function	Hormone Activity Corticotropin-releasing Hormone Receptor Binding Corticotropin-releasing Hormone Receptor 2 Binding	Cytokine Receptor Activity Interleukin-10 Receptor Activity Protein Binding Signaling Receptor Activity
	Biological Process	Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Digestion Response To Glucose Hormone-mediated Signaling Pathway Cellular Response To Nutrient Levels Positive Regulation Of Insulin Secretion Response To Immobilization Stress Response To Starvation Positive Regulation Of Membrane Potential Response To Corticosterone Cellular Response To Hypoxia	Inflammatory Response Immune Response Signal Transduction Cytokine-mediated Signaling Pathway Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Defense Response To Virus
Pathways		Class B/2 (Secretin family receptors)	Other interleukin signaling Interleukin-10 signaling Interleukin-20 family signaling
Drugs
Diseases
GWAS		Intelligence ( 22449649)	Blood protein levels ( 30072576) Crohn's disease ( 23128233) Multiple sclerosis ( 31604244) Narcolepsy ( 24204295 23459209)
Interacting Genes		3 interacting genes: CRHR1 CRHR2 IL10RB	7 interacting genes: IFNL2 IFNL3 IL10 IL10RA IL22 UCN2 UCN3
Entrez ID		114131	3588
HPRD ID		12066	00473
Ensembl ID		ENSG00000178473	ENSG00000243646
Uniprot IDs		Q969E3	Q08334
PDB IDs		2RMH 3N93	3LQM 5T5W
Enriched GO Terms of Interacting Partners?
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