Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
CHRNA1 and ITGA7
Data Source:
HPRD
(in vivo)
CHRNA1
ITGA7
Description
cholinergic receptor nicotinic alpha 1 subunit
integrin subunit alpha 7
Image
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
Acetylcholine-gated Channel Complex
Cell Surface
Neuromuscular Junction
Neuron Projection
Synapse
Postsynaptic Membrane
Integral Component Of Postsynaptic Specialization Membrane
Plasma Membrane
Integrin Complex
Cell Surface
Molecular Function
Ion Channel Activity
Acetylcholine Receptor Activity
Acetylcholine-gated Cation-selective Channel Activity
Neurotransmitter Receptor Activity
Acetylcholine Binding
Transmitter-gated Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential
Protein Binding
Metal Ion Binding
Biological Process
Skeletal Muscle Contraction
Cation Transport
Signal Transduction
Chemical Synaptic Transmission
Synaptic Transmission, Cholinergic
Neuromuscular Synaptic Transmission
Neuromuscular Junction Development
Neuronal Action Potential
Ion Transmembrane Transport
Regulation Of Membrane Potential
Muscle Cell Cellular Homeostasis
Skeletal Muscle Tissue Growth
Nervous System Process
Musculoskeletal Movement
Neuromuscular Process
Excitatory Postsynaptic Potential
Neuron Cellular Homeostasis
Cell-matrix Adhesion
Integrin-mediated Signaling Pathway
Muscle Organ Development
Regulation Of Cell Shape
Extracellular Matrix Organization
Heterotypic Cell-cell Adhesion
Endodermal Cell Differentiation
Pathways
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
Highly calcium permeable nicotinic acetylcholine receptors
Integrin cell surface interactions
Laminin interactions
Laminin interactions
ECM proteoglycans
Drugs
Lamotrigine
Agmatine
Diseases
Congenital myasthenic syndrome
Multiple pterygium syndrome, including: Multiple pterygium syndrome, lethal type (LMPS); Multiple pterygium syndrome, Escobar variant (EVMPS)
Congenital muscular dystrophies (CMD/MDC), including: Merosin-deficient CMD (MDC1A); Ullrich CMD (UCMD); Integrin alpha7-deficient CMD; CMD with joint hyperlaxity (CMDH); CMD with epidermolysis bullosa; Walker-Warburg syndrome (WWS); Muscle-eye-brain disease (MEB); Fukuyama CMD (FCMD); CMD with muscle hypertrophy (MDC1C); CMD with severe intellectual impairment and abnormal glycosylation (MDC1D); Rigid spine syndrome (RSS); LMNA-deficient CMD; CMD with respiratory failure and muscle hypertrophy (MDC1B); Bethlem myopathy
GWAS
Atrial fibrillation (
29892015
)
Post bronchodilator FEV1/FVC ratio (
26634245
)
Refractive error (
32231278
)
Interacting Genes
5 interacting genes:
CHRND
CHRNE
CHRNG
ITGA7
LILRB3
4 interacting genes:
CHRNA1
FHL2
FHL3
MYOC
Entrez ID
1134
3679
HPRD ID
00007
02761
Ensembl ID
ENSG00000138435
ENSG00000135424
Uniprot IDs
P02708
Q53SH4
Q13683
Q4LE35
PDB IDs
1Y5P
1Y5T
1Y6C
4ZJS
5HBT
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?