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CHRNA1 and CHRNE
Data Source:
HPRD
(in vitro)
CHRNA1
CHRNE
Description
cholinergic receptor nicotinic alpha 1 subunit
cholinergic receptor nicotinic epsilon subunit
Image
GO Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
Acetylcholine-gated Channel Complex
Cell Surface
Neuromuscular Junction
Neuron Projection
Synapse
Postsynaptic Membrane
Integral Component Of Postsynaptic Specialization Membrane
Plasma Membrane
Integral Component Of Plasma Membrane
Acetylcholine-gated Channel Complex
Neuromuscular Junction
Neuron Projection
Synapse
Postsynaptic Membrane
Molecular Function
Ion Channel Activity
Acetylcholine Receptor Activity
Acetylcholine-gated Cation-selective Channel Activity
Neurotransmitter Receptor Activity
Acetylcholine Binding
Transmitter-gated Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential
Cation Transmembrane Transporter Activity
Acetylcholine Receptor Activity
Acetylcholine-gated Cation-selective Channel Activity
Neurotransmitter Receptor Activity
Transmitter-gated Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential
Biological Process
Skeletal Muscle Contraction
Cation Transport
Signal Transduction
Chemical Synaptic Transmission
Synaptic Transmission, Cholinergic
Neuromuscular Synaptic Transmission
Neuromuscular Junction Development
Neuronal Action Potential
Ion Transmembrane Transport
Regulation Of Membrane Potential
Muscle Cell Cellular Homeostasis
Skeletal Muscle Tissue Growth
Nervous System Process
Musculoskeletal Movement
Neuromuscular Process
Excitatory Postsynaptic Potential
Neuron Cellular Homeostasis
Muscle Contraction
Signal Transduction
Chemical Synaptic Transmission
Synaptic Transmission, Cholinergic
Ion Transmembrane Transport
Regulation Of Membrane Potential
Nervous System Process
Excitatory Postsynaptic Potential
Cation Transmembrane Transport
Pathways
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
Highly calcium permeable nicotinic acetylcholine receptors
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors
Drugs
Lamotrigine
Agmatine
Diseases
Congenital myasthenic syndrome
Multiple pterygium syndrome, including: Multiple pterygium syndrome, lethal type (LMPS); Multiple pterygium syndrome, Escobar variant (EVMPS)
Congenital myasthenic syndrome
GWAS
Atrial fibrillation (
29892015
)
Platelet count (
29403010
)
Interacting Genes
5 interacting genes:
CHRND
CHRNE
CHRNG
ITGA7
LILRB3
1 interacting genes:
CHRNA1
Entrez ID
1134
1145
HPRD ID
00007
00008
Ensembl ID
ENSG00000138435
ENSG00000108556
Uniprot IDs
P02708
Q53SH4
Q04844
PDB IDs
1Y5P
1Y5T
1Y6C
4ZJS
5HBT
2DF9
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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