VPS45 and RAB13

Data Source:
BioGRID (two hybrid)

		VPS45	RAB13
Description		vacuolar protein sorting 45 homolog	RAB13, member RAS oncogene family
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cellular_component Golgi Apparatus Endosome Membrane Integral Component Of Membrane	Endosome Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Bicellular Tight Junction Synaptic Vesicle Lateral Plasma Membrane Lamellipodium Cell Junction Endocytic Vesicle Trans-Golgi Network Transport Vesicle Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Insulin-responsive Compartment Neuron Projection Recycling Endosome Recycling Endosome Membrane Extracellular Exosome
	Molecular Function	Molecular_function Protein Binding	GTPase Activity Protein Binding GTP Binding
	Biological Process	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Blood Coagulation Vesicle-mediated Transport	Vesicle Docking Involved In Exocytosis Protein Secretion Protein Kinase A Signaling Endosomal Transport Regulation Of Exocytosis Cortical Actin Cytoskeleton Organization Neuron Projection Development Endocytic Recycling Cellular Response To Insulin Stimulus Endothelial Cell Chemotaxis Post-translational Protein Modification Trans-Golgi Network To Recycling Endosome Transport Golgi Vesicle Fusion To Target Membrane Bicellular Tight Junction Assembly Protein Localization To Plasma Membrane Establishment Of Sertoli Cell Barrier
Pathways		Intra-Golgi traffic Factors involved in megakaryocyte development and platelet production	Translocation of SLC2A4 (GLUT4) to the plasma membrane RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Bipolar disorder ( 31043756) Broad depression or schizophrenia ( 30626913) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Obesity in adult survivors of childhood cancer not exposed to cranial radiation ( 25963547) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656) Uric acid levels ( 21294900)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cooked vegetable consumption ( 32066663) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		11 interacting genes: BCAR3 CASP8 IGF1R PAX2 PTPN1 RB1CC1 RBSN SNTG1 STX16 VPS11 VPS18	10 interacting genes: APP MICALL1 PDE6D RAB11A RAB7A RAB8A RABGAP1L SMAD4 SMURF2 TGFBR1
Entrez ID		11311	5872
HPRD ID		10301	04053
Ensembl ID		ENSG00000136631	ENSG00000143545
Uniprot IDs		A0A2R8YE10 B7Z360 B7Z5D4 Q9NRW7	A0A087WWB9 P51153 Q504R6
PDB IDs
Enriched GO Terms of Interacting Partners?
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