VPS45 and RPRD2

Data Source:
BioGRID (biochemical)

		VPS45	RPRD2
Description		vacuolar protein sorting 45 homolog	regulation of nuclear pre-mRNA domain containing 2
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cellular_component Golgi Apparatus Endosome Membrane Integral Component Of Membrane	Nucleoplasm RNA Polymerase II, Holoenzyme
	Molecular Function	Molecular_function Protein Binding	RNA Polymerase II Complex Binding
	Biological Process	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Blood Coagulation Vesicle-mediated Transport	MRNA 3'-end Processing SnRNA Transcription By RNA Polymerase II
Pathways		Intra-Golgi traffic Factors involved in megakaryocyte development and platelet production	RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Bipolar disorder ( 31043756) Broad depression or schizophrenia ( 30626913) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Obesity in adult survivors of childhood cancer not exposed to cranial radiation ( 25963547) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656) Uric acid levels ( 21294900)	Bitter non-alcoholic beverage consumption ( 31046077) Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Broad depression or bipolar disorder ( 30626913) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Neutrophil count ( 32888494) Refractive error ( 32231278) Schizophrenia ( 28991256) Spontaneous coronary artery dissection ( 32887874) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		11 interacting genes: BCAR3 CASP8 IGF1R PAX2 PTPN1 RB1CC1 RBSN SNTG1 STX16 VPS11 VPS18	6 interacting genes: CSNK2A1 MTNR1B PPP1CA PPP1CC SPOP UPF1
Entrez ID		11311	23248
HPRD ID		10301	11084
Ensembl ID		ENSG00000136631	ENSG00000163125
Uniprot IDs		A0A2R8YE10 B7Z360 B7Z5D4 Q9NRW7	Q5VT52
PDB IDs			4FLB
Enriched GO Terms of Interacting Partners?
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