PMF1 and COPS7B

Data Source:
HPRD (two hybrid)

		PMF1	COPS7B
Description		polyamine modulated factor 1	COP9 signalosome subunit 7B
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GO Annotations	Cellular Component	MIS12/MIND Type Complex Condensed Chromosome Kinetochore Nuclear MIS12/MIND Complex Nucleoplasm Transcription Regulator Complex Golgi Apparatus Cytosol Intracellular Membrane-bounded Organelle	Nucleoplasm Cytosol COP9 Signalosome
	Molecular Function	Transcription Coactivator Activity Protein Binding Leucine Zipper Domain Binding	Protein Binding
	Biological Process	Transcription By RNA Polymerase II Cell Cycle Chromosome Segregation Positive Regulation Of Transcription, DNA-templated Cell Division	Protein Deneddylation Nucleotide-excision Repair, DNA Damage Recognition Transcription-coupled Nucleotide-excision Repair COP9 Signalosome Assembly Viral Process Post-translational Protein Modification
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	DNA Damage Recognition in GG-NER Formation of TC-NER Pre-Incision Complex Cargo recognition for clathrin-mediated endocytosis Neddylation
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 30604766) Intracerebral hemorrhage ( 24656865) Ischemic stroke ( 29531354) Ischemic stroke (small-vessel) ( 29531354) Longevity (age >99th survival percentile) ( 31413261) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269) Non-lobar intracerebral hemorrhage (MTAG) ( 31430377) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Stroke ( 29531354) White matter hyperintensity burden ( 25663218)	Height ( 18391951)
Interacting Genes		24 interacting genes: BICD2 CEP126 COPS6 COPS7A COPS7B CRMP1 DSN1 EFHC1 FBXO28 GDF9 GIT1 HSP90AA1 KDM1A MED31 MESD MIS12 NFE2L2 PTN SHC3 SUGT1 TBC1D21 TCP10L TSNAX USHBP1	11 interacting genes: APP BEX5 COPS2 COPS3 COPS4 COPS5 COPS6 EIF3E GPS1 NMI PMF1
Entrez ID		11243	64708
HPRD ID		11441	09889
Ensembl ID		ENSG00000160783	ENSG00000144524
Uniprot IDs		Q6P1K2	A0A024R471 A0A024R478 A0A087X1P5 J3KQ34 J3KQ41 Q6ZTQ7 Q9H9Q2
PDB IDs		5LSJ 5LSK	6R6H 6R7F 6R7H 6R7I 6R7N
Enriched GO Terms of Interacting Partners?
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