RPL35 and LAMC3

Data Source:
BioGRID (two hybrid)

		RPL35	LAMC3
Description		ribosomal protein L35	laminin subunit gamma 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleolus Cytosol Membrane Cytosolic Large Ribosomal Subunit	Extracellular Region Basement Membrane Membrane Extracellular Matrix
	Molecular Function	RNA Binding MRNA Binding Structural Constituent Of Ribosome	Structural Molecule Activity
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Maturation Of LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription	Visual Perception Animal Organ Morphogenesis Tissue Development Astrocyte Development Cell Migration Extracellular Matrix Organization Substrate Adhesion-dependent Cell Spreading Retina Development In Camera-type Eye
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions MET activates PTK2 signaling
Drugs		Artenimol
Diseases
GWAS			Alcohol consumption (max-drinks) ( 29460428) Deep ovarian and/or rectovaginal disease with dense adhesions ( 28333195) Degraded stimulus continuous performance test score ( 31596458) Endometriosis ( 28333195) Oral cavity and pharyngeal cancer ( 27749845) Oral cavity cancer ( 27749845) Smoking status (heavy vs never) ( 26423011)
Interacting Genes		9 interacting genes: ACTN2 ADH4 CDKN1A CREBBP DUX4 LAMC3 MAX SGSM3 TUBB2B	20 interacting genes: ANXA5 CFB CRP CSNK2A2 CWC25 CYP2E1 EPB41L4B FRAT1 HP KIF1C LGMN NR1H2 PELI2 POT1 RPL35 SERPINA3 SLC43A3 TF YTHDC1 ZNF160
Entrez ID		11224	10319
HPRD ID		10200	05069
Ensembl ID		ENSG00000136942	ENSG00000050555
Uniprot IDs		P42766	Q8N2D6 Q9Y6N6
PDB IDs		4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6SXO 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO
Enriched GO Terms of Interacting Partners?
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