LAMC3 and ANXA5

Data Source:
BioGRID (two hybrid)

		LAMC3	ANXA5
Description		laminin subunit gamma 3	annexin A5
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Basement Membrane Membrane Extracellular Matrix	Extracellular Region Cytoplasm Cytosol Focal Adhesion Membrane Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Structural Molecule Activity	Phospholipase Inhibitor Activity Calcium Ion Binding Protein Binding Phospholipid Binding Calcium-dependent Phospholipid Binding
	Biological Process	Visual Perception Animal Organ Morphogenesis Tissue Development Astrocyte Development Cell Migration Extracellular Matrix Organization Substrate Adhesion-dependent Cell Spreading Retina Development In Camera-type Eye	Platelet Degranulation Signal Transduction Blood Coagulation Negative Regulation Of Apoptotic Process Negative Regulation Of Catalytic Activity Negative Regulation Of Coagulation
Pathways		Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions MET activates PTK2 signaling	Platelet degranulation
Drugs			Fluocinolone acetonide L-Alpha-Glycerophosphorylserine L-thioproline K201 free base sn-glycero-3-phosphoethanolamine 1,4-Dideoxy-O2-Sulfo-Glucuronic Acid N,O6-Disulfo-Glucosamine 1,4-Dideoxy-5-Dehydro-O2-Sulfo-Glucuronic Acid Copper
Diseases
GWAS		Alcohol consumption (max-drinks) ( 29460428) Deep ovarian and/or rectovaginal disease with dense adhesions ( 28333195) Degraded stimulus continuous performance test score ( 31596458) Endometriosis ( 28333195) Oral cavity and pharyngeal cancer ( 27749845) Oral cavity cancer ( 27749845) Smoking status (heavy vs never) ( 26423011)	Age at smoking initiation in chronic obstructive pulmonary disease ( 21685187) Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Resting-state electroencephalogram vigilance ( 29703947)
Interacting Genes		20 interacting genes: ANXA5 CFB CRP CSNK2A2 CWC25 CYP2E1 EPB41L4B FRAT1 HP KIF1C LGMN NR1H2 PELI2 POT1 RPL35 SERPINA3 SLC43A3 TF YTHDC1 ZNF160	19 interacting genes: ACTG1 APP COL10A1 COL2A1 EED EIF4G1 FDFT1 GSC2 IFNGR2 ITGB5 KDR LAMC3 LINC01554 PPP2R1B SUPT4H1 TERF1 TERF2 TERF2IP TINF2
Entrez ID		10319	308
HPRD ID		05069	00568
Ensembl ID		ENSG00000050555	ENSG00000164111
Uniprot IDs		Q8N2D6 Q9Y6N6	P08758 V9HWE0
PDB IDs			1ANW 1ANX 1AVH 1AVR 1HAK 1HVD 1HVE 1HVF 1HVG 1SAV 2XO2 2XO3 6K22 6K25
Enriched GO Terms of Interacting Partners?
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