CHKA and RCC1

Data Source:
HPRD (in vivo, in vitro)

		CHKA	RCC1
Description		choline kinase alpha	regulator of chromosome condensation 1
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GO Annotations	Cellular Component	Cytosol	Chromatin Condensed Nuclear Chromosome Nucleus Nucleoplasm Cytoplasm Nuclear Membrane Protein-containing Complex
	Molecular Function	Choline Kinase Activity Cholinesterase Activity Ethanolamine Kinase Activity ATP Binding Drug Binding Choline Binding Identical Protein Binding	Chromatin Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding Small GTPase Binding Nucleosome Binding Nucleosomal DNA Binding Histone Binding Sulfate Binding Protein Heterodimerization Activity
	Biological Process	Ethanolamine Metabolic Process Lipid Metabolic Process Phosphatidylethanolamine Biosynthetic Process Phosphatidylcholine Biosynthetic Process CDP-choline Pathway Lipid Transport Response To Toxic Substance Phosphorylation Choline Metabolic Process Response To 3-methylcholanthrene	G1/S Transition Of Mitotic Cell Cycle Mitotic Spindle Organization Chromosome Segregation Regulation Of Mitotic Nuclear Division Viral Process Ran Protein Signal Transduction Regulation Of Catalytic Activity Spindle Assembly Cell Division Regulation Of Mitotic Spindle Assembly
Pathways		Synthesis of PC Synthesis of PE	Rev-mediated nuclear export of HIV RNA Nuclear import of Rev protein Postmitotic nuclear pore complex (NPC) reformation
Drugs
Diseases
GWAS			Night sleep phenotypes ( 27126917) Systolic blood pressure ( 30578418)
Interacting Genes		6 interacting genes: APP DEPTOR FCHSD2 PSEN2 RCC1 SKP2	50 interacting genes: ACTB APLP1 BAG6 CCT7 CDK1 CDK2AP2 CHGB CHKA CSAD CSNK1A1 DDAH2 DYNC1I1 ERCC6 FAF1 FBXO7 FLAD1 GNB2 H2AC18 H2AC20 H2BC21 H3C1 HADHB HMGA1 HOXD8 KMT2B KPNA3 KPNA4 LRIF1 NGFR NTMT1 NUDT21 NUP98 PDHB PKM PTMA RAN RANBP1 RANBP3 RPA1 SDF4 SPRED1 SUMO2 TLE1 TRMT2A TUBB3 UNC119 USP4 WIZ XPO1 ZNF135
Entrez ID		1119	1104
HPRD ID		00327	01559
Ensembl ID		ENSG00000110721	ENSG00000180198
Uniprot IDs		P35790	A0A0S2Z3I4 A0A0S2Z404 P18754 Q5T081
PDB IDs		2CKO 2CKP 2CKQ 2I7Q 3F2R 3G15 3ZM9 4BR3 4CG8 4CG9 4CGA 4DA5 5AFV 5EQE 5EQP 5EQY 5FTG 5FUT 5W6O 7A04 7A06	1A12 1I2M 5E1B 5E1D 5E1M 5E1O 5E2A 5E2B 5TBK 6DUB
Enriched GO Terms of Interacting Partners?
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