RCC1 and NTMT1

Data Source:
BioGRID (enzymatic study)

		RCC1	NTMT1
Description		regulator of chromosome condensation 1	N-terminal Xaa-Pro-Lys N-methyltransferase 1
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GO Annotations	Cellular Component	Chromatin Condensed Nuclear Chromosome Nucleus Nucleoplasm Cytoplasm Nuclear Membrane Protein-containing Complex	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Chromatin Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding Small GTPase Binding Nucleosome Binding Nucleosomal DNA Binding Histone Binding Sulfate Binding Protein Heterodimerization Activity	Protein Binding Methyltransferase Activity Protein Methyltransferase Activity Histone Methyltransferase Activity N-terminal Protein N-methyltransferase Activity
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Mitotic Spindle Organization Chromosome Segregation Regulation Of Mitotic Nuclear Division Viral Process Ran Protein Signal Transduction Regulation Of Catalytic Activity Spindle Assembly Cell Division Regulation Of Mitotic Spindle Assembly	N-terminal Protein Amino Acid Methylation Spindle Organization Chromosome Segregation Histone Methylation N-terminal Peptidyl-alanine Methylation N-terminal Peptidyl-alanine Trimethylation N-terminal Peptidyl-glycine Methylation N-terminal Peptidyl-proline Dimethylation N-terminal Peptidyl-proline Methylation N-terminal Peptidyl-serine Methylation N-terminal Peptidyl-serine Dimethylation N-terminal Peptidyl-serine Trimethylation
Pathways		Rev-mediated nuclear export of HIV RNA Nuclear import of Rev protein Postmitotic nuclear pore complex (NPC) reformation
Drugs
Diseases
GWAS		Night sleep phenotypes ( 27126917) Systolic blood pressure ( 30578418)
Interacting Genes		50 interacting genes: ACTB APLP1 BAG6 CCT7 CDK1 CDK2AP2 CHGB CHKA CSAD CSNK1A1 DDAH2 DYNC1I1 ERCC6 FAF1 FBXO7 FLAD1 GNB2 H2AC18 H2AC20 H2BC21 H3C1 HADHB HMGA1 HOXD8 KMT2B KPNA3 KPNA4 LRIF1 NGFR NTMT1 NUDT21 NUP98 PDHB PKM PTMA RAN RANBP1 RANBP3 RPA1 SDF4 SPRED1 SUMO2 TLE1 TRMT2A TUBB3 UNC119 USP4 WIZ XPO1 ZNF135	7 interacting genes: APP DDB2 DIS3 GLYR1 HNRNPD IKBKG RCC1
Entrez ID		1104	28989
HPRD ID		01559	10628
Ensembl ID		ENSG00000180198	ENSG00000148335
Uniprot IDs		A0A0S2Z3I4 A0A0S2Z404 P18754 Q5T081	A0A024R8E4 Q9BV86 S4R338
PDB IDs		1A12 1I2M 5E1B 5E1D 5E1M 5E1O 5E2A 5E2B 5TBK 6DUB	2EX4 5CVD 5CVE 5E1B 5E1D 5E1M 5E1O 5E2A 5E2B 6DTN 6KDQ 6PVA 6PVB 6WH8 6WJ7
Enriched GO Terms of Interacting Partners?
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