ZNF277 and CDCA8

Data Source:
BioGRID (two hybrid)

		ZNF277	CDCA8
Description		zinc finger protein 277	cell division cycle associated 8
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Chromosome, Centromeric Region Nucleoplasm Nucleolus Cytosol Chromocenter Midbody Chromosome Passenger Complex Protein-containing Complex Intercellular Bridge Spindle Midzone
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Metal Ion Binding	Protein Binding
	Biological Process	Cellular Response To Hydrogen Peroxide Regulation Of Cellular Senescence	Mitotic Sister Chromatid Segregation Mitotic Metaphase Plate Congression Chromosome Organization Cell Division
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion SUMOylation of DNA replication proteins RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Breast size ( 22747683) Early-onset Parkinson's disease ( 28256260) Refractive error ( 32231278)	Axial length ( 24144296) Eyebrow thickness ( 26926045)
Interacting Genes		9 interacting genes: CDCA8 COIL DDB1 GNGT1 MBD3 NUTM1 RPP14 ZBTB7B ZNF768	26 interacting genes: AURKB BIRC5 EMILIN1 FBXO17 GYS1 H3C14 HLA-DRB3 HMBOX1 INCENP MAPKAPK5 NEK3 NKAPD1 NTAQ1 PIAS2 PIH1D2 RANBP2 RPRD1B SENP3 SET SGO1 SGO2 SNAPC5 SPANXN2 TTK UBE2I ZNF277
Entrez ID		11179	55143
HPRD ID		05680	13017
Ensembl ID		ENSG00000198839	ENSG00000134690
Uniprot IDs		Q9NRM2	Q53HL2
PDB IDs			2KDD 2QFA 2RAW 2RAX 6YIE 6YIF 6YIH
Enriched GO Terms of Interacting Partners?
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