BAZ2A and SMARCA5

Data Source:
HPRD (in vivo, in vitro)

		BAZ2A	SMARCA5
Description		bromodomain adjacent to zinc finger domain 2A	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
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GO Annotations	Cellular Component	Chromatin Silencing Complex Nucleolus Cytosol Nuclear Speck RDNA Heterochromatin	Condensed Chromosome Fibrillar Center Nucleus Nucleoplasm Chromatin Silencing Complex Cytosol NURF Complex RSF Complex Intracellular Membrane-bounded Organelle Nuclear Replication Fork
	Molecular Function	RNA Polymerase I Core Promoter Sequence-specific DNA Binding RNA Binding Protein Binding Nuclear Receptor Binding Histone Binding Metal Ion Binding Lysine-acetylated Histone Binding	DNA Binding Helicase Activity Protein Binding ATP Binding DNA-dependent ATPase Activity ATPase Activity Nucleosome Binding Histone Binding
	Biological Process	RDNA Heterochromatin Assembly RNA Polymerase I Preinitiation Complex Assembly DNA Methylation Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription, DNA-templated Histone Deacetylation	RDNA Heterochromatin Assembly Nucleosome Assembly Chromatin Remodeling DNA-templated Transcription, Initiation Regulation Of Transcription By RNA Polymerase II Nucleosome Positioning CENP-A Containing Nucleosome Assembly ATP-dependent Chromatin Remodeling Positive Regulation Of Gene Expression, Epigenetic Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Leukemia Inhibitory Factor
Pathways		NoRC negatively regulates rRNA expression	NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Deposition of new CENPA-containing nucleosomes at the centromere
Drugs			Beta-D-Glucose 4-Deoxy-Alpha-D-Glucose
Diseases
GWAS		Mean platelet volume ( 22139419 32888494 27863252) Platelet count ( 22139419 32888494) Platelet distribution width ( 32888494)	Height ( 31562340) Malaria ( 31844061)
Interacting Genes		8 interacting genes: ADRB2 DNMT1 DNMT3B H4C1 HDAC1 KAT8 SMARCA5 TTF1	18 interacting genes: BAZ1A BAZ1B BAZ2A CDT1 CHRAC1 CREB1 CTNNB1 DNMT3B H3-3A H3C1 H4-16 HDAC2 MAF POLE3 PTEN RAD21 RSF1 SATB1
Entrez ID		11176	8467
HPRD ID		10417	04538
Ensembl ID		ENSG00000076108	ENSG00000153147
Uniprot IDs		F8VU39 Q9UIF9	O60264
PDB IDs		4LZ2 4Q6F 4QBM 4QF2 5AGQ 5MGJ 5MGK 5MGL 5MGM 5OR8 5T8R 6FAP 6FG6 6FGF 6FGG 6FGH 6FGI 6FGL 6FGV 6FGW 6FHU 6FI0 6FKP	6NE3
Enriched GO Terms of Interacting Partners?
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