DIDO1 and SRSF1

Data Source:
BioGRID (two hybrid)

		DIDO1	SRSF1
Description		death inducer-obliterator 1	serine and arginine rich splicing factor 1
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GO Annotations	Cellular Component	Nucleus Cytoplasm Spindle	Nucleus Nucleoplasm Cytoplasm Nuclear Speck Exon-exon Junction Complex Catalytic Step 2 Spliceosome
	Molecular Function	RNA Binding Metal Ion Binding	RNA Binding MRNA Binding Protein Binding DNA Topoisomerase Binding
	Biological Process	Transcription, DNA-templated Apoptotic Signaling Pathway	Alternative MRNA Splicing, Via Spliceosome MRNA 5'-splice Site Recognition MRNA Splicing, Via Spliceosome MRNA Splice Site Selection MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus MRNA 3'-end Processing
Pathways			Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs			Copper
Diseases
GWAS		Mean corpuscular volume ( 32888494) Menopause (age at onset) ( 26414677)	Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
Interacting Genes		12 interacting genes: APP ARAF DVL3 H3-4 HNRNPK KCNK4 LRRK2 SRPK2 SRSF1 SUMO2 WWP1 WWP2	43 interacting genes: AKAP17A APP BCL10 C1QBP CACNA1A CD8A CDC42 CDK12 CDK6 CLK1 DIDO1 DYRK1A GEMIN2 HIPK3 HNRNPA0 LNX1 LUC7L3 NFYA NXF1 PPARG PRPF4 PRPF4B PSIP1 RNPS1 SCAF11 SNRNP70 SREK1 SRPK1 SRPK2 SRSF10 SRSF11 SRSF4 SRSF5 TCERG1 TNPO3 TOP1 TP53 TRA2B U2AF1 U2AF2 XBP1 YTHDC1 ZRSR2
Entrez ID		11083	6426
HPRD ID		10363	02887
Ensembl ID		ENSG00000101191	ENSG00000136450
Uniprot IDs		Q9BTC0	Q07955 Q59FA2
PDB IDs		2M3H 4L7X	1X4A 2M7S 2M8D 2O3D 3BEG 4C0O
Enriched GO Terms of Interacting Partners?
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