TMEM115 and RASSF1

Data Source:
HPRD (in vivo)

		TMEM115	RASSF1
Description		transmembrane protein 115	Ras association domain family member 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleus Golgi Apparatus Integral Component Of Membrane Golgi Transport Complex Golgi Cisterna Membrane	Spindle Pole Nucleus Cytoplasm Microtubule Organizing Center Microtubule Microtubule Cytoskeleton
	Molecular Function	Molecular_function Protein Binding Identical Protein Binding	Protein Binding Zinc Ion Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Negative Regulation Of Cell Population Proliferation Protein Transport	Cell Cycle Arrest Signal Transduction Ras Protein Signal Transduction Regulation Of Microtubule Cytoskeleton Organization
Pathways		COPI-mediated anterograde transport
Drugs
Diseases			Non-small cell lung cancer Bladder cancer Nasopharyngeal cancer
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Basophil percentage of white cells ( 32888494) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) High light scatter reticulocyte count ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Schizophrenia ( 28991256 30285260) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		12 interacting genes: AQP6 ASPG CREB3 CYB5R3 HTATIP2 MANBAL RABAC1 SYNE4 TLCD4 TMED8 TMX2 ZDHHC17	70 interacting genes: AKT1 ARAF ATM ATP2B4 ATR ATRX AURKA AURKB BRAF C7orf25 C8orf33 CCND2 CCNE1 CDC20 CDK4 CDK6 CDKN2A CDKN2B CLNK CNKSR1 DAXX DDB1 E4F1 EPHA2 ERBB2 EXOSC8 FGFR4 FZR1 GLIS2 GRM1 HRAS IGFBP5 KAT2A KCNE3 KDELR2 KDM1A LATS2 MAP1B MAP1S MAP2K3 MAP2K6 MAPK8 MDM2 MET MOAP1 MST1 MYC NF2 NUDT10 PRKDC RAF1 RASSF5 RELA RHOA RHOU SAV1 SMARCA4 STK11 STK3 STK4 SUV39H1 SUV39H2 TEAD2 TERT TNFRSF10A TNFRSF1A TSC1 TUBB TUBG1 XPA
Entrez ID		11070	11186
HPRD ID		06144	05470
Ensembl ID		ENSG00000126062	ENSG00000068028
Uniprot IDs		A0A024R2Y2 Q12893	Q9NS23
PDB IDs			2KZU
Enriched GO Terms of Interacting Partners?
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