DSTN and SSH1

Data Source:
BioGRID (enzymatic study)

		DSTN	SSH1
Description		destrin, actin depolymerizing factor	slingshot protein phosphatase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Actin Cytoskeleton Cortical Actin Cytoskeleton Extracellular Exosome	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Lamellipodium Growth Cone Midbody Cleavage Furrow Synapse
	Molecular Function	Protein Binding Actin Filament Binding	Actin Binding Phosphoprotein Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity
	Biological Process	Actin Polymerization Or Depolymerization Actin Filament Depolymerization Actin Filament Fragmentation Positive Regulation Of Actin Filament Depolymerization Cell Motility Actin Filament Severing	Cell Morphogenesis Protein Dephosphorylation Actin Cytoskeleton Organization Negative Regulation Of Actin Filament Polymerization Positive Regulation Of Synaptic Plasticity Regulation Of Cellular Protein Metabolic Process Peptidyl-tyrosine Dephosphorylation Cellular Response To ATP Excitatory Chemical Synaptic Transmission Positive Regulation Of Neuron Death Positive Regulation Of AMPA Glutamate Receptor Clustering Positive Regulation Of Vascular Associated Smooth Muscle Cell Migration Positive Regulation Of Excitatory Postsynaptic Potential
Pathways
Drugs		Dodecyldimethylamine N-oxide
Diseases
GWAS		Coronary artery disease ( 29212778) Presence of antiphospholipid antibodies ( 23509613)	Brain morphology (MOSTest) ( 32665545) Mean platelet volume ( 27863252) Platelet count ( 32888494)
Interacting Genes		8 interacting genes: ACTB ACTG1 CFL2 SHBG SMAD9 SSH1 TAX1BP1 TESK2	6 interacting genes: ACTB AKT1 CFL1 CFL2 CORO1B DSTN
Entrez ID		11034	54434
HPRD ID		16446	09486
Ensembl ID		ENSG00000125868	ENSG00000084112
Uniprot IDs		P60981 V9HWA6	Q8WYL5
PDB IDs
Enriched GO Terms of Interacting Partners?
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