SSH1 and CORO1B

Data Source:
HPRD (in vitro, in vivo)

		SSH1	CORO1B
Description		slingshot protein phosphatase 1	coronin 1B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Lamellipodium Growth Cone Midbody Cleavage Furrow Synapse	Stress Fiber Cytoplasm Cytosol Actin Filament Plasma Membrane Focal Adhesion Lamellipodium Cell Leading Edge Perinuclear Region Of Cytoplasm Extracellular Exosome Cell Periphery
	Molecular Function	Actin Binding Phosphoprotein Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity	Protein Binding Identical Protein Binding Cadherin Binding Actin Filament Binding Arp2/3 Complex Binding
	Biological Process	Cell Morphogenesis Protein Dephosphorylation Actin Cytoskeleton Organization Negative Regulation Of Actin Filament Polymerization Positive Regulation Of Synaptic Plasticity Regulation Of Cellular Protein Metabolic Process Peptidyl-tyrosine Dephosphorylation Cellular Response To ATP Excitatory Chemical Synaptic Transmission Positive Regulation Of Neuron Death Positive Regulation Of AMPA Glutamate Receptor Clustering Positive Regulation Of Vascular Associated Smooth Muscle Cell Migration Positive Regulation Of Excitatory Postsynaptic Potential	Actin Filament Organization Cell Migration Actin Cytoskeleton Organization Ruffle Organization Regulation Of Arp2/3 Complex-mediated Actin Nucleation Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Endothelial Cell Chemotaxis Cellular Response To Platelet-derived Growth Factor Stimulus Wound Healing Actin Filament Bundle Assembly Negative Regulation Of Smooth Muscle Cell Chemotaxis Actin Filament Branching Protein Localization To Cell Leading Edge Positive Regulation Of Lamellipodium Morphogenesis
Pathways
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Mean platelet volume ( 27863252) Platelet count ( 32888494)	HDL cholesterol levels ( 32203549) Non-response to citalopram or escitalopram and depression ( 27622933) Refractive error ( 32231278)
Interacting Genes		6 interacting genes: ACTB AKT1 CFL1 CFL2 CORO1B DSTN	8 interacting genes: ARPC2 KPNA2 LHX4 POLR1C PRKCA SSH1 TERF1 TRIM15
Entrez ID		54434	57175
HPRD ID		09486	16743
Ensembl ID		ENSG00000084112	ENSG00000172725
Uniprot IDs		Q8WYL5	A0A024R5K1 Q9BR76
PDB IDs
Enriched GO Terms of Interacting Partners?
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