CHAT and KCNQ3

Data Source:
BioGRID (genetic interference)

		CHAT	KCNQ3
Description		choline O-acetyltransferase	potassium voltage-gated channel subfamily Q member 3
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Neuron Projection Presynapse	Plasma Membrane Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex Cell Surface Integral Component Of Membrane Node Of Ranvier Axon Initial Segment Synapse
	Molecular Function	Choline O-acetyltransferase Activity	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Protein Binding Calmodulin Binding
	Biological Process	Phosphatidylcholine Biosynthetic Process Neurotransmitter Secretion Neuromuscular Synaptic Transmission Acetylcholine Biosynthetic Process	Chemical Synaptic Transmission Regulation Of Ion Transmembrane Transport Membrane Hyperpolarization Potassium Ion Transmembrane Transport
Pathways		Synthesis of PC Acetylcholine Neurotransmitter Release Cycle	Voltage gated Potassium channels Interaction between L1 and Ankyrins
Drugs		Nicotine	Enflurane Amitriptyline Meclofenamic acid Gabapentin Promethazine Miconazole Ezogabine ICA-105665
Diseases		Congenital myasthenic syndrome
GWAS		Glaucoma (primary angle closure) ( 27064256) Interleukin-1-receptor antagonist levels ( 22205395) Pulse pressure x alcohol consumption interaction (2df test) ( 29912962) Type 2 diabetes nephropathy ( 30566433)	Coronary artery calcification ( 23870195) Height ( 28552196) LDL peak particle diameter (total fat intake interaction) ( 26112879) QT interval ( 29213071) Type 2 diabetes ( 31324766)
Interacting Genes		9 interacting genes: CAMK2A CAMK2G NEDD9 PRKCA PRKCB PRKCD PRKCE PRKCG PRKCZ	6 interacting genes: CALM1 CALM2 CALM3 KCNQ2 KCNQ4 KCNQ5
Entrez ID		1103	3786
HPRD ID		07510	09077
Ensembl ID		ENSG00000070748	ENSG00000184156
Uniprot IDs		D3DX95 P28329 Q6LEN5 Q6LEN6	O43525
PDB IDs		2FY2 2FY3 2FY4 2FY5 7AMD	5J03
Enriched GO Terms of Interacting Partners?
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