KCNQ3 and KCNQ5

Data Source:
HPRD (in vivo)

		KCNQ3	KCNQ5
Description		potassium voltage-gated channel subfamily Q member 3	potassium voltage-gated channel subfamily Q member 5
Image
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex Cell Surface Integral Component Of Membrane Node Of Ranvier Axon Initial Segment Synapse	Plasma Membrane Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex Integral Component Of Membrane Clathrin Coat
	Molecular Function	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Protein Binding Calmodulin Binding	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Protein Binding Calmodulin Binding
	Biological Process	Chemical Synaptic Transmission Regulation Of Ion Transmembrane Transport Membrane Hyperpolarization Potassium Ion Transmembrane Transport	Regulation Of Ion Transmembrane Transport Potassium Ion Transmembrane Transport
Pathways		Voltage gated Potassium channels Interaction between L1 and Ankyrins	Voltage gated Potassium channels
Drugs		Enflurane Amitriptyline Meclofenamic acid Gabapentin Promethazine Miconazole Ezogabine ICA-105665	Enflurane Gabapentin Promethazine Miconazole Ezogabine ICA-105665
Diseases
GWAS		Coronary artery calcification ( 23870195) Height ( 28552196) LDL peak particle diameter (total fat intake interaction) ( 26112879) QT interval ( 29213071) Type 2 diabetes ( 31324766)	Carotid plaque burden ( 28282560) Frontal pole volume ( 31530798) High myopia ( 31816047) HIV-1 viral setpoint ( 26039976) Lung function (FEV1/FVC) ( 28166213 30804560) Lung function (FVC) ( 30804560) Myopia ( 27182965) Optic disc size ( 31809533) Peak expiratory flow ( 30804560) Periodontitis ( 25672891) Plasma proprotein convertase subtilisin/kexin type 9 levels in stable coronary artery disease ( 29748315) Pulse pressure ( 30224653) Refractive error ( 23396134 32231278) Rosacea symptom severity ( 29771307) Spherical equivalent (joint analysis main effects and education interaction) ( 27020472) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Total body bone mineral density ( 30172743) Upper eyelid sagging severity ( 24869959) Western dietary pattern ( 28644415)
Interacting Genes		6 interacting genes: CALM1 CALM2 CALM3 KCNQ2 KCNQ4 KCNQ5	7 interacting genes: CALM1 CALM2 CALM3 DISC1 KCNQ3 MTDH SRC
Entrez ID		3786	56479
HPRD ID		09077	16241
Ensembl ID		ENSG00000184156	ENSG00000185760
Uniprot IDs		O43525	Q9NR82
PDB IDs		5J03	6B8Q
Enriched GO Terms of Interacting Partners?
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